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Head-to-head · WeighScore

BetterMe Rx vs Rylo Health

BetterMe Rx
Graded #235

Higher grade

vs+0.20000000000000284
Rylo Health
Graded #240

Lower grade

The verdict

BetterMe Rx takes it — 64.9/100 to 64.7/100, but only just.

BetterMe Rx grades higher on WeighScore, our editorial score across cost value, dose & formulation, clinical oversight, labs & monitoring, fulfillment and contract terms. BetterMe Rx offers compounded semaglutide ($199/mo) and tirzepatide ($299/mo) in both injectable and oral daily tablet formats. Rylo Health is close behind and may still be the better fit — see the factor split below.

We may earn a commission if you start care through some of these links, at no extra cost to you. It never moves the WeighScore, which is the weighted average of the six factors shown for every provider, and what we write about a provider is the same either way. See our disclosure.

Factor by factor

The same six graded dimensions, side by side. See the methodology.

Cost valueRylo Health +20
44
64
Dose & formulationBetterMe Rx +11
75
64
Clinical oversightBetterMe Rx +9
84
75
Labs & monitoringRylo Health +1
52
53
FulfillmentBetterMe Rx +5
88
83
Contract termsBetterMe Rx +10
47
37
BetterMe Rx · left barRylo Health · right bar

The numbers

MetricBetterMe RxRylo Health
WeighScore64.9/10064.7/100
GradeCC
Scorecard rank#235#240
Semaglutide$199/mo (promotional rate, compounded)$149/mo (promotional rate, compounded)
Tirzepatide$299/mo (promotional rate, compounded)$249/mo (compounded)
CoverageAll 50 statesAll 50 states
Brand-name accessCompounded onlyCompounded only
Oral / sublingualYesInjection only
BetterMe Rx

Graded #235 · C

Strengths

  • LegitScript verified
  • All 50 states coverage
  • Six named pharmacy partners with phone numbers — exceptional transparency
  • Both injectable and oral daily tablet formats for sema and tirz
  • Multi-month discounts (3-month and 6-month plans)

Where it loses points

  • No formal corporate entity name or address disclosed
  • Compounded only — no brand-name options
  • Broader platform (HRT, ED, NAD+, Sermorelin, skincare)
  • Headline $199/$299 are limited-time SALE prices; regular prices are $249/$349 per month
Rylo Health

Graded #240 · C

Strengths

  • Names its dispensing pharmacy in full, with address and phone: VialsRX in Houston, Texas
  • Names its medical group, Lone Star Virtual Health PLLC, and gives a provider contact
  • Standard prices published openly alongside the promotional rate, so the real ongoing cost is visible
  • Cancel in one click from the patient portal, with no contracts and no cancellation fees
  • Peptide line priced openly, including NAD+ and sermorelin

Where it loses points

  • Headline $100 and $160 rates are limited to the first 20 patients; standard rates are $149 and $249
  • No LegitScript certification is claimed or displayed
  • Several peptide products are advertised as coming soon rather than available
  • No published refund policy beyond the no-cancellation-fee statement

Also worth a look

Neither is our top-graded pick — CoreAge Rx leads the scorecard

Across all 499 providers, CoreAge Rx grades highest at 91.8/100 (A−). Top of the scorecard: flat transparent pricing, both molecules, nationwide — no teaser-rate games.

Pricing/verification reflect each provider's public disclosures at last grading; the WeighScore is our editorial judgment per the methodology. Prices change — confirm on each provider's site. Not medical advice; see our disclosure.

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