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Head-to-head · WeighScore

Avono Health vs Trimrose

Avono Health
Graded #369

Higher grade

vs+3.299999999999997
Trimrose
Graded #446

Lower grade

The verdict

Avono Health takes it — 58.5/100 to 55.2/100.

Avono Health grades higher on WeighScore, our editorial score across cost value, dose & formulation, clinical oversight, labs & monitoring, fulfillment and contract terms. Fully online compounded GLP-1 telehealth with transparent, tiered pricing — microdose and standard semaglutide and tirzepatide in both injection and oral forms — plus US-licensed clinicians, 24/7 messaging…

We may earn a commission if you start care through some of these links, at no extra cost to you. It never moves the WeighScore, which is the weighted average of the six factors shown for every provider, and what we write about a provider is the same either way. See our disclosure.

Factor by factor

The same six graded dimensions, side by side. See the methodology.

Cost valueTrimrose +10
29
39
Dose & formulationAvono Health +11
75
64
Clinical oversightAvono Health +12
80
68
Labs & monitoringAvono Health +1
53
52
FulfillmentAvono Health +14
71
57
Contract termsTrimrose +8
47
55
Avono Health · left barTrimrose · right bar

The numbers

MetricAvono HealthTrimrose
WeighScore58.5/10055.2/100
GradeCC
Scorecard rank#369#446
Semaglutide$269/mo (compounded)Not disclosed
Tirzepatide$349/mo (compounded)Not disclosed
CoverageCoverage not publishedCoverage not published
Brand-name accessCompounded onlyYes
Oral / sublingualYesYes
Avono Health

Graded #369 · C

Strengths

  • Transparent tiered pricing from $179/mo (microdose semaglutide injection)
  • Full compounded range — semaglutide and tirzepatide, injection and oral, microdose and standard
  • Free and discreet shipping; 24/7/365 messaging support; 100% online
  • US-licensed clinicians and pharmacies; bundle discounts at 3/6/12 months

Where it loses points

  • Medications are compounded, not FDA-approved brand-name
  • Compounding pharmacy not publicly named
  • State availability not published
  • Newer brand with limited independent review history
Trimrose

Graded #446 · C

Strengths

  • Free, no-cost, no-obligation online eligibility quiz before any commitment
  • Offers a choice of a weekly compounded GLP-1 injection or a daily oral option
  • Fully online — assessment, provider review, and home delivery with ongoing support

Where it loses points

  • Runs on the CareValidate white-label platform and isn't the medical provider itself — a support@carevalidate.com address is exposed on the site
  • Pricing isn't shown publicly; the cost and the specific compounded molecule appear only after you complete the eligibility quiz
  • The states served, pharmacy partner and any LegitScript/503A certification aren't disclosed on the public site
  • Markets 'up to 22.5% of body weight' — a trial figure for branded tirzepatide, not a guaranteed or compounded-specific outcome
  • Compounded GLP-1s are not FDA-reviewed or approved — a different evidence and regulatory tier than brand-name

Also worth a look

Neither is our top-graded pick — CoreAge Rx leads the scorecard

Across all 499 providers, CoreAge Rx grades highest at 91.8/100 (A−). Top of the scorecard: flat transparent pricing, both molecules, nationwide — no teaser-rate games.

Pricing/verification reflect each provider's public disclosures at last grading; the WeighScore is our editorial judgment per the methodology. Prices change — confirm on each provider's site. Not medical advice; see our disclosure.

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