Head-to-head · WeighScore
Avono Health vs SynergenX Health
The verdict
Avono Health takes it — 58.7/100 to 58.4/100, but only just.
Avono Health grades higher on WeighScore, our editorial score across cost value, dose & formulation, clinical oversight, labs & monitoring, fulfillment and contract terms. Fully online compounded GLP-1 telehealth with transparent, tiered pricing — microdose and standard semaglutide and tirzepatide in both injection and oral forms — plus US-licensed clinicians, 24/7 messaging… SynergenX Health is close behind and may still be the better fit — see the factor split below.
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Factor by factor
The same six graded dimensions, side by side. See the methodology.
The numbers
| Metric | Avono Health | SynergenX Health |
|---|---|---|
| WeighScore | 58.7/100 | 58.4/100 |
| Grade | C | C |
| Scorecard rank | #361 | #374 |
| Semaglutide | $269/mo (compounded) | $150/mo (starting dose, plus a separate fee, compounded) |
| Tirzepatide | $349/mo (compounded) | Not disclosed |
| Coverage | Coverage not published | 10 states |
| Brand-name access | Compounded only | Compounded only |
| Oral / sublingual | Yes | Injection only |
Graded #361 · C
Strengths
- Transparent tiered pricing from $179/mo (microdose semaglutide injection)
- Full compounded range — semaglutide and tirzepatide, injection and oral, microdose and standard
- Free and discreet shipping; 24/7/365 messaging support; 100% online
- US-licensed clinicians and pharmacies; bundle discounts at 3/6/12 months
Where it loses points
- Medications are compounded, not FDA-approved brand-name
- Compounding pharmacy not publicly named
- State availability not published
- Newer brand with limited independent review history
Graded #374 · C
Strengths
- Compounded semaglutide from $150/mo including medication and refrigerated home shipping — no hidden fees stated on site
- Backed by 64-clinic chain operating across 10 states with medical providers for in-person or telehealth care
- Telehealth consultations from home; $100 initial visit, $40 follow-up every 1–3 months
- Nutrition counseling and lifestyle planning included as part of personalized treatment program
- Free weight-loss consultation option available before committing to paid evaluation
Where it loses points
- Telehealth GLP-1 program currently Texas-only; rolling out more states but no timeline published
- Tirzepatide not confirmed for online program; only compounded semaglutide explicitly listed
- Labs not included or mentioned; no baseline bloodwork protocol disclosed on website
- Dose-escalation pricing not published; $150/mo is entry dose only, higher doses may cost more
- No LegitScript, named medical director, or publicly disclosed compounding pharmacy partner found
Also worth a look
Neither is our top-graded pick — CoreAge Rx leads the scorecard
Across all 499 providers, CoreAge Rx grades highest at 91.8/100 (A−). Top of the scorecard: flat transparent pricing, both molecules, nationwide — no teaser-rate games.
Pricing/verification reflect each provider's public disclosures at last grading; the WeighScore is our editorial judgment per the methodology. Prices change — confirm on each provider's site. Not medical advice; see our disclosure.