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Head-to-head · WeighScore

Avono Health vs PCOS Sisters

Avono Health
Graded #369

Lower grade

vs+7.200000000000003
PCOS Sisters
Graded #218

Higher grade

The verdict

PCOS Sisters takes it — 65.7/100 to 58.5/100.

PCOS Sisters grades higher on WeighScore, our editorial score across cost value, dose & formulation, clinical oversight, labs & monitoring, fulfillment and contract terms. PCOS Sisters is a women's telehealth clinic focused on polycystic ovary syndrome that offers a GLP-1 weight and metabolic management program for 150 dollars per month with membership required.

We may earn a commission if you start care through some of these links, at no extra cost to you. It never moves the WeighScore, which is the weighted average of the six factors shown for every provider, and what we write about a provider is the same either way. See our disclosure.

Factor by factor

The same six graded dimensions, side by side. See the methodology.

Cost valuePCOS Sisters +32
29
61
Dose & formulationPCOS Sisters +13
75
88
Clinical oversightAvono Health +10
80
70
Labs & monitoringAvono Health +1
53
52
FulfillmentAvono Health +6
71
65
Contract termsAvono Health +6
47
41
Avono Health · left barPCOS Sisters · right bar

The numbers

MetricAvono HealthPCOS Sisters
WeighScore58.5/10065.7/100
GradeCC
Scorecard rank#369#218
Semaglutide$269/mo (compounded)$150/mo (plus a separate fee, compounded)
Tirzepatide$349/mo (compounded)$150/mo (plus a separate fee, compounded)
CoverageCoverage not published12 states
Brand-name accessCompounded onlyYes
Oral / sublingualYesYes
Avono Health

Graded #369 · C

Strengths

  • Transparent tiered pricing from $179/mo (microdose semaglutide injection)
  • Full compounded range — semaglutide and tirzepatide, injection and oral, microdose and standard
  • Free and discreet shipping; 24/7/365 messaging support; 100% online
  • US-licensed clinicians and pharmacies; bundle discounts at 3/6/12 months

Where it loses points

  • Medications are compounded, not FDA-approved brand-name
  • Compounding pharmacy not publicly named
  • State availability not published
  • Newer brand with limited independent review history
PCOS Sisters

Graded #218 · C

Strengths

  • Dedicated PCOS specialty model with metabolic program and fitness app included
  • Transparent 150 dollars per month GLP-1 management fee
  • Names real partner pharmacies (Strive, Striker) and lists phone support

Where it loses points

  • Only 12 states served
  • Membership required on top of the medical program
  • Unclear whether pharmacy dispensing fees are separate from the 150/mo fee

Also worth a look

Neither is our top-graded pick — CoreAge Rx leads the scorecard

Across all 499 providers, CoreAge Rx grades highest at 91.8/100 (A−). Top of the scorecard: flat transparent pricing, both molecules, nationwide — no teaser-rate games.

Pricing/verification reflect each provider's public disclosures at last grading; the WeighScore is our editorial judgment per the methodology. Prices change — confirm on each provider's site. Not medical advice; see our disclosure.

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