Head-to-head · WeighScore
Avono Health vs Nucore Health
The verdict
Avono Health takes it — 58.7/100 to 58.6/100, but only just.
Avono Health grades higher on WeighScore, our editorial score across cost value, dose & formulation, clinical oversight, labs & monitoring, fulfillment and contract terms. Fully online compounded GLP-1 telehealth with transparent, tiered pricing — microdose and standard semaglutide and tirzepatide in both injection and oral forms — plus US-licensed clinicians, 24/7 messaging… Nucore Health is close behind and may still be the better fit — see the factor split below.
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Factor by factor
The same six graded dimensions, side by side. See the methodology.
The numbers
| Metric | Avono Health | Nucore Health |
|---|---|---|
| WeighScore | 58.7/100 | 58.6/100 |
| Grade | C | C |
| Scorecard rank | #361 | #367 |
| Semaglutide | $269/mo (compounded) | $299/mo (starting dose, compounded) |
| Tirzepatide | $349/mo (compounded) | $199/mo (microdose tier, compounded) |
| Coverage | Coverage not published | Coverage not published |
| Brand-name access | Compounded only | Compounded only |
| Oral / sublingual | Yes | Injection only |
Graded #361 · C
Strengths
- Transparent tiered pricing from $179/mo (microdose semaglutide injection)
- Full compounded range — semaglutide and tirzepatide, injection and oral, microdose and standard
- Free and discreet shipping; 24/7/365 messaging support; 100% online
- US-licensed clinicians and pharmacies; bundle discounts at 3/6/12 months
Where it loses points
- Medications are compounded, not FDA-approved brand-name
- Compounding pharmacy not publicly named
- State availability not published
- Newer brand with limited independent review history
Graded #367 · C
Strengths
- Physician-owned and LegitScript Certified — strong trust signals
- Available nationwide in all 50 states
- Care and pharmacy fulfillment run on OpenLoop Health's licensed network
- Broad menu — compounded GLP-1, microdose tirzepatide, NAD+, sermorelin, MIC B12
Where it loses points
- Published pricing is gated behind the intake quiz — no upfront cost shown
- Legal terms and privacy are posted as downloadable documents, not web pages
- Compounded GLP-1 is not FDA-approved and prescribed off-label (per their own notice)
- Longevity and microdose positioning is marketing; evidence varies by use
Also worth a look
Neither is our top-graded pick — CoreAge Rx leads the scorecard
Across all 499 providers, CoreAge Rx grades highest at 91.8/100 (A−). Top of the scorecard: flat transparent pricing, both molecules, nationwide — no teaser-rate games.
Pricing/verification reflect each provider's public disclosures at last grading; the WeighScore is our editorial judgment per the methodology. Prices change — confirm on each provider's site. Not medical advice; see our disclosure.