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Head-to-head · WeighScore

Avono Health vs Medsol RX

Avono Health
Graded #361

Lower grade

vs+2.299999999999997
Medsol RX
Graded #306

Higher grade

The verdict

Medsol RX takes it — 61/100 to 58.7/100.

Medsol RX grades higher on WeighScore, our editorial score across cost value, dose & formulation, clinical oversight, labs & monitoring, fulfillment and contract terms. Medsol RX is a GLP-1 weight-loss telehealth program offering compounded semaglutide (from $209/mo) and tirzepatide, prescribed by board-certified clinicians via OpenLoop and shipped nationwide.

We may earn a commission if you start care through some of these links, at no extra cost to you. It never moves the WeighScore, which is the weighted average of the six factors shown for every provider, and what we write about a provider is the same either way. See our disclosure.

Factor by factor

The same six graded dimensions, side by side. See the methodology.

Cost valueMedsol RX +15
30
45
Dose & formulationAvono Health +11
75
64
Clinical oversightAvono Health +1
80
79
Labs & monitoringEven
53
53
FulfillmentMedsol RX +12
71
83
Contract termsAvono Health +6
47
41
Avono Health · left barMedsol RX · right bar

The numbers

MetricAvono HealthMedsol RX
WeighScore58.7/10061/100
GradeCC
Scorecard rank#361#306
Semaglutide$269/mo (compounded)$209/mo (compounded)
Tirzepatide$349/mo (compounded)$250/mo (compounded)
CoverageCoverage not publishedAll 50 states
Brand-name accessCompounded onlyCompounded only
Oral / sublingualYesInjection only
Avono Health

Graded #361 · C

Strengths

  • Transparent tiered pricing from $179/mo (microdose semaglutide injection)
  • Full compounded range — semaglutide and tirzepatide, injection and oral, microdose and standard
  • Free and discreet shipping; 24/7/365 messaging support; 100% online
  • US-licensed clinicians and pharmacies; bundle discounts at 3/6/12 months

Where it loses points

  • Medications are compounded, not FDA-approved brand-name
  • Compounding pharmacy not publicly named
  • State availability not published
  • Newer brand with limited independent review history
Medsol RX

Graded #306 · C

Strengths

  • Compounded semaglutide from $209/mo (12-mo plan) and tirzepatide from ~$250/mo; HSA/FSA eligible with Klarna financing
  • Every plan bundles the medication, a dedicated care coach, custom treatment plan, medical oversight, and free shipping
  • Board-certified clinicians via OpenLoop; same-day approvals; ships nationwide
  • Month-to-month option ($199 first month) with no long-term commitment, plus microdosing and wellness add-ons

Where it loses points

  • Doesn't name its compounding pharmacy (generic 'certified U.S. pharmacies')
  • No legal entity name published on the site
  • Tirzepatide pricing is given as a range ($250-$1,400/mo), not a fixed rate
  • Compounded GLP-1s are not FDA-approved (the site discloses this)

Also worth a look

Neither is our top-graded pick — CoreAge Rx leads the scorecard

Across all 499 providers, CoreAge Rx grades highest at 91.8/100 (A−). Top of the scorecard: flat transparent pricing, both molecules, nationwide — no teaser-rate games.

Pricing/verification reflect each provider's public disclosures at last grading; the WeighScore is our editorial judgment per the methodology. Prices change — confirm on each provider's site. Not medical advice; see our disclosure.

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