Head-to-head · WeighScore
Avono Health vs MediRX
The verdict
MediRX takes it — 66.1/100 to 58.7/100.
MediRX grades higher on WeighScore, our editorial score across cost value, dose & formulation, clinical oversight, labs & monitoring, fulfillment and contract terms. MediRX is a telehealth weight-loss platform offering compounded GLP-1 injections — semaglutide starting at $149/month and tirzepatide starting at $199/month — plus NAD+ and a name-brand GLP-1 option.
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Factor by factor
The same six graded dimensions, side by side. See the methodology.
The numbers
| Metric | Avono Health | MediRX |
|---|---|---|
| WeighScore | 58.7/100 | 66.1/100 |
| Grade | C | C |
| Scorecard rank | #361 | #206 |
| Semaglutide | $269/mo (compounded) | $149/mo (compounded) |
| Tirzepatide | $349/mo (compounded) | $199/mo (compounded) |
| Coverage | Coverage not published | Coverage not published |
| Brand-name access | Compounded only | Yes |
| Oral / sublingual | Yes | Injection only |
Graded #361 · C
Strengths
- Transparent tiered pricing from $179/mo (microdose semaglutide injection)
- Full compounded range — semaglutide and tirzepatide, injection and oral, microdose and standard
- Free and discreet shipping; 24/7/365 messaging support; 100% online
- US-licensed clinicians and pharmacies; bundle discounts at 3/6/12 months
Where it loses points
- Medications are compounded, not FDA-approved brand-name
- Compounding pharmacy not publicly named
- State availability not published
- Newer brand with limited independent review history
Graded #206 · C
Strengths
- LegitScript Certified — a meaningful trust signal for an online pharmacy
- Named operating entity disclosed (MediRX, Inc., Wyoming)
- Care and pharmacy fulfillment run on OpenLoop Health's licensed network
- Low promotional first-month pricing — semaglutide first month as low as $70
Where it loses points
- Doesn't publish the exact states it serves; telehealth rules vary by state
- Ongoing monthly price rises after the promotional first month
- Compounded semaglutide and tirzepatide injections — limited oral options
- Specific compounding pharmacies aren't named beyond the OpenLoop network
Also worth a look
Neither is our top-graded pick — CoreAge Rx leads the scorecard
Across all 499 providers, CoreAge Rx grades highest at 91.8/100 (A−). Top of the scorecard: flat transparent pricing, both molecules, nationwide — no teaser-rate games.
Pricing/verification reflect each provider's public disclosures at last grading; the WeighScore is our editorial judgment per the methodology. Prices change — confirm on each provider's site. Not medical advice; see our disclosure.