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Head-to-head · WeighScore

Aspire Health vs SynergenX Health

Aspire Health
Graded #346

Higher grade

vs+1.1000000000000014
SynergenX Health
Graded #380

Lower grade

The verdict

Aspire Health takes it — 59.2/100 to 58.1/100, but only just.

Aspire Health grades higher on WeighScore, our editorial score across cost value, dose & formulation, clinical oversight, labs & monitoring, fulfillment and contract terms. Aspire Health is a Nebraska-based telehealth practice offering both compounded semaglutide/tirzepatide (formulated with B6) and brand-name Wegovy and Zepbound, prescribed by a named PA/NP clinical team. SynergenX Health is close behind and may still be the better fit — see the factor split below.

We may earn a commission if you start care through some of these links, at no extra cost to you. It never moves the WeighScore, which is the weighted average of the six factors shown for every provider, and what we write about a provider is the same either way. See our disclosure.

Factor by factor

The same six graded dimensions, side by side. See the methodology.

Cost valueEven
45
45
Dose & formulationAspire Health +1
53
52
Clinical oversightAspire Health +18
84
66
Labs & monitoringSynergenX Health +20
66
86
FulfillmentAspire Health +6
61
55
Contract termsSynergenX Health +6
41
47
Aspire Health · left barSynergenX Health · right bar

The numbers

MetricAspire HealthSynergenX Health
WeighScore59.2/10058.1/100
GradeCC
Scorecard rank#346#380
SemaglutideNot disclosed$150/mo (starting dose, plus a separate fee, compounded)
TirzepatideNot disclosedNot disclosed
CoverageCoverage not published10 states
Brand-name accessYesCompounded only
Oral / sublingualInjection onlyInjection only
Aspire Health

Graded #346 · C

Strengths

  • Both compounded and brand-name options (Wegovy + Zepbound) — rare among GLP-1 telehealth providers
  • Lab orders with interpretation included in LoseIt membership — not billed separately
  • Named clinical team: founded by Jenni Haan, MPAS, PA-C (18+ years experience) with four additional credentialed providers
  • Slimpossible app + secure messaging for ongoing support between provider visits
  • HSA/FSA accepted; Cherry third-party financing available for patients needing payment plans

Where it loses points

  • Membership fee ($75/month) stacks on top of separately billed medication — total spend $205–$524/month depending on dose
  • No LegitScript certification or independent third-party accreditation disclosed
  • States served not publicly listed; availability depends on individual provider licensure
  • All medication sales are final once shipped; consultation fee non-refundable once completed
  • Compounding pharmacy partner not named on any public page
SynergenX Health

Graded #380 · C

Strengths

  • Compounded semaglutide from $150/mo including medication and refrigerated home shipping — no hidden fees stated on site
  • Backed by 64-clinic chain operating across 10 states with medical providers for in-person or telehealth care
  • Telehealth consultations from home; $100 initial visit, $40 follow-up every 1–3 months
  • Nutrition counseling and lifestyle planning included as part of personalized treatment program
  • Free weight-loss consultation option available before committing to paid evaluation

Where it loses points

  • Telehealth GLP-1 program currently Texas-only; rolling out more states but no timeline published
  • Tirzepatide not confirmed for online program; only compounded semaglutide explicitly listed
  • Labs not included or mentioned; no baseline bloodwork protocol disclosed on website
  • Dose-escalation pricing not published; $150/mo is entry dose only, higher doses may cost more
  • No LegitScript, named medical director, or publicly disclosed compounding pharmacy partner found

Also worth a look

Neither is our top-graded pick — CoreAge Rx leads the scorecard

Across all 499 providers, CoreAge Rx grades highest at 91.8/100 (A−). Top of the scorecard: flat transparent pricing, both molecules, nationwide — no teaser-rate games.

Pricing/verification reflect each provider's public disclosures at last grading; the WeighScore is our editorial judgment per the methodology. Prices change — confirm on each provider's site. Not medical advice; see our disclosure.

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