Head-to-head · WeighScore
Aspire Health vs Defy Medical
The verdict
Defy Medical takes it — 60.2/100 to 59.2/100, but only just.
Defy Medical grades higher on WeighScore, our editorial score across cost value, dose & formulation, clinical oversight, labs & monitoring, fulfillment and contract terms. Defy Medical is a long-running telehealth clinic, best known for hormone replacement, that also prescribes GLP-1 medications for weight loss. Aspire Health is close behind and may still be the better fit — see the factor split below.
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Factor by factor
The same six graded dimensions, side by side. See the methodology.
The numbers
| Metric | Aspire Health | Defy Medical |
|---|---|---|
| WeighScore | 59.2/100 | 60.2/100 |
| Grade | C | C |
| Scorecard rank | #346 | #325 |
| Semaglutide | Not disclosed | Not disclosed |
| Tirzepatide | Not disclosed | Not disclosed |
| Coverage | Coverage not published | Coverage not published |
| Brand-name access | Yes | Compounded only |
| Oral / sublingual | Injection only | Yes |
Graded #346 · C
Strengths
- Both compounded and brand-name options (Wegovy + Zepbound) — rare among GLP-1 telehealth providers
- Lab orders with interpretation included in LoseIt membership — not billed separately
- Named clinical team: founded by Jenni Haan, MPAS, PA-C (18+ years experience) with four additional credentialed providers
- Slimpossible app + secure messaging for ongoing support between provider visits
- HSA/FSA accepted; Cherry third-party financing available for patients needing payment plans
Where it loses points
- Membership fee ($75/month) stacks on top of separately billed medication — total spend $205–$524/month depending on dose
- No LegitScript certification or independent third-party accreditation disclosed
- States served not publicly listed; availability depends on individual provider licensure
- All medication sales are final once shipped; consultation fee non-refundable once completed
- Compounding pharmacy partner not named on any public page
Graded #325 · C
Strengths
- Multiple GLP-1 options: semaglutide, tirzepatide, liraglutide
- Offers injection, ODT, and oral drop delivery forms
- Comprehensive blood testing and named medical director
- Established clinic with strong Trustpilot review volume
Where it loses points
- GLP-1 pricing not published on the website
- States served and shipping limits not disclosed
- Compounded versus brand status not stated online
- Lab-heavy, consult-first model may cost more upfront
Also worth a look
Neither is our top-graded pick — CoreAge Rx leads the scorecard
Across all 499 providers, CoreAge Rx grades highest at 91.8/100 (A−). Top of the scorecard: flat transparent pricing, both molecules, nationwide — no teaser-rate games.
Pricing/verification reflect each provider's public disclosures at last grading; the WeighScore is our editorial judgment per the methodology. Prices change — confirm on each provider's site. Not medical advice; see our disclosure.