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Head-to-head · WeighScore

Ascend Vitality vs Youth & Soul

Ascend Vitality
Graded #307

Lower grade

vs+0.7000000000000028
Youth & Soul
Graded #291

Higher grade

The verdict

Youth & Soul takes it — 61.6/100 to 60.9/100, but only just.

Youth & Soul grades higher on WeighScore, our editorial score across cost value, dose & formulation, clinical oversight, labs & monitoring, fulfillment and contract terms. Ten-vertical telehealth marketplace selling compounded GLP-1 tiers alongside HRT, ED, nootropics and peptides, running on the Bask Health platform. Ascend Vitality is close behind and may still be the better fit — see the factor split below.

We may earn a commission if you start care through some of these links, at no extra cost to you. It never moves the WeighScore, which is the weighted average of the six factors shown for every provider, and what we write about a provider is the same either way. See our disclosure.

Factor by factor

The same six graded dimensions, side by side. See the methodology.

Cost valueYouth & Soul +24
50
74
Dose & formulationAscend Vitality +11
75
64
Clinical oversightAscend Vitality +20
74
54
Labs & monitoringYouth & Soul +8
52
60
FulfillmentAscend Vitality +10
65
55
Contract termsYouth & Soul +12
37
49
Ascend Vitality · left barYouth & Soul · right bar

The numbers

MetricAscend VitalityYouth & Soul
WeighScore60.9/10061.6/100
GradeCC
Scorecard rank#307#291
Semaglutide$199/mo (compounded)$149/mo (starting dose, compounded)
Tirzepatide$299/mo (compounded)$399/mo (compounded)
CoverageCoverage not publishedCoverage not published
Brand-name accessCompounded onlyCompounded only
Oral / sublingualYesInjection only
Ascend Vitality

Graded #307 · C

Strengths

  • Both injectable and needle-free oral tablet forms of semaglutide and tirzepatide
  • LegitScript certified
  • Transparent cash-pay pricing with cancel-anytime subscription
  • Legal entity and address publicly disclosed (Ascend Vitality LLC, Sheridan, WY)

Where it loses points

  • All medications are compounded — FDA does not review compounded drugs for safety/effectiveness
  • No named compounding pharmacy partner disclosed
  • No public state-by-state availability list (homepage cites exclusions: LA, MS, KS, NM, WV)
  • Per-dose/titration pricing not published; only 'starting at' prices shown
Youth & Soul

Graded #291 · C

Strengths

  • Three GLP-1 tiers priced openly, with the dose range and every included component listed per tier
  • Full refund advertised if you are not approved
  • Physician consultation, prescription and shipping stated as included in the plan price
  • Ten treatment verticals under one account, from GLP-1 to HRT, peptides and mental health

Where it loses points

  • Describes its compounded medications as FDA-Approved Compounds, which is false: compounded drugs are not FDA-approved
  • Presents scraped third-party comments as testimonials, several using Reddit usernames and some describing brand Wegovy or Mounjaro
  • Its own copy promises never to fabricate testimonials while displaying those scraped comments
  • Homepage trust counters render as 0K+ medical professionals, 0.0M+ patients and 0M+ successful orders
  • Labels its compounded tirzepatide a Mounjaro compound, conflating a compounded drug with the brand

Also worth a look

Neither is our top-graded pick — CoreAge Rx leads the scorecard

Across all 499 providers, CoreAge Rx grades highest at 91.8/100 (A−). Top of the scorecard: flat transparent pricing, both molecules, nationwide — no teaser-rate games.

Pricing/verification reflect each provider's public disclosures at last grading; the WeighScore is our editorial judgment per the methodology. Prices change — confirm on each provider's site. Not medical advice; see our disclosure.

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