Head-to-head · WeighScore
Ascend Vitality vs Tryozi
The verdict
Tryozi takes it — 61.4/100 to 60.9/100, but only just.
Tryozi grades higher on WeighScore, our editorial score across cost value, dose & formulation, clinical oversight, labs & monitoring, fulfillment and contract terms. Florida telehealth selling compounded GLP-1 injections at a flat price that does not rise with dose, naming all four of its 503A compounding pharmacies. Ascend Vitality is close behind and may still be the better fit — see the factor split below.
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Factor by factor
The same six graded dimensions, side by side. See the methodology.
The numbers
| Metric | Ascend Vitality | Tryozi |
|---|---|---|
| WeighScore | 60.9/100 | 61.4/100 |
| Grade | C | C |
| Scorecard rank | #307 | #295 |
| Semaglutide | $199/mo (compounded) | $279/mo (compounded) |
| Tirzepatide | $299/mo (compounded) | $379/mo (compounded) |
| Coverage | Coverage not published | All 50 states |
| Brand-name access | Compounded only | Compounded only |
| Oral / sublingual | Yes | Injection only |
Graded #307 · C
Strengths
- Both injectable and needle-free oral tablet forms of semaglutide and tirzepatide
- LegitScript certified
- Transparent cash-pay pricing with cancel-anytime subscription
- Legal entity and address publicly disclosed (Ascend Vitality LLC, Sheridan, WY)
Where it loses points
- All medications are compounded — FDA does not review compounded drugs for safety/effectiveness
- No named compounding pharmacy partner disclosed
- No public state-by-state availability list (homepage cites exclusions: LA, MS, KS, NM, WV)
- Per-dose/titration pricing not published; only 'starting at' prices shown
Graded #295 · C
Strengths
- Names all four of its 503A compounding pharmacies: RedRock, Health Warehouse, Precision Medicine and Triad Rx
- Price does not increase as your dose increases, stated plainly on the pricing page
- Full total shown before payment, with the first-month discount and the ongoing rate both visible
- States plainly that compounded medications are not FDA-approved, a disclosure many competitors omit
- LegitScript certification verified against the issued seal, not just the badge
Where it loses points
- Headline $139 is a first-month half-price offer; the ongoing rate is $279
- Multi-week plans are billed once as a single upfront charge, not as a lower monthly rate
- Plans ship every 4 weeks, so a 52-week plan is 13 shipments rather than 12 months
- No refund policy detail is published on the pricing page itself
Also worth a look
Neither is our top-graded pick — CoreAge Rx leads the scorecard
Across all 499 providers, CoreAge Rx grades highest at 91.8/100 (A−). Top of the scorecard: flat transparent pricing, both molecules, nationwide — no teaser-rate games.
Pricing/verification reflect each provider's public disclosures at last grading; the WeighScore is our editorial judgment per the methodology. Prices change — confirm on each provider's site. Not medical advice; see our disclosure.