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Head-to-head · WeighScore

Ascend Vitality vs Optimized Health

Ascend Vitality
Graded #307

Lower grade

vs+6.300000000000004
Optimized Health
Graded #166

Higher grade

The verdict

Optimized Health takes it — 67.2/100 to 60.9/100.

Optimized Health grades higher on WeighScore, our editorial score across cost value, dose & formulation, clinical oversight, labs & monitoring, fulfillment and contract terms. Optimized Health is a concierge medical weight loss and hormone clinic offering clinician-supervised GLP-1 programs with compounded semaglutide and tirzepatide, plus oral options like phentermine.

We may earn a commission if you start care through some of these links, at no extra cost to you. It never moves the WeighScore, which is the weighted average of the six factors shown for every provider, and what we write about a provider is the same either way. See our disclosure.

Factor by factor

The same six graded dimensions, side by side. See the methodology.

Cost valueAscend Vitality +5
50
45
Dose & formulationEven
75
75
Clinical oversightOptimized Health +2
74
76
Labs & monitoringOptimized Health +37
52
89
FulfillmentOptimized Health +2
65
67
Contract termsOptimized Health +18
37
55
Ascend Vitality · left barOptimized Health · right bar

The numbers

MetricAscend VitalityOptimized Health
WeighScore60.9/10067.2/100
GradeCC
Scorecard rank#307#166
Semaglutide$199/mo (compounded)$200/mo (starting dose, compounded)
Tirzepatide$299/mo (compounded)$250/mo (starting dose, compounded)
CoverageCoverage not published5 states
Brand-name accessCompounded onlyCompounded only
Oral / sublingualYesYes
Ascend Vitality

Graded #307 · C

Strengths

  • Both injectable and needle-free oral tablet forms of semaglutide and tirzepatide
  • LegitScript certified
  • Transparent cash-pay pricing with cancel-anytime subscription
  • Legal entity and address publicly disclosed (Ascend Vitality LLC, Sheridan, WY)

Where it loses points

  • All medications are compounded — FDA does not review compounded drugs for safety/effectiveness
  • No named compounding pharmacy partner disclosed
  • No public state-by-state availability list (homepage cites exclusions: LA, MS, KS, NM, WV)
  • Per-dose/titration pricing not published; only 'starting at' prices shown
Optimized Health

Graded #166 · C

Strengths

  • Fully transparent pricing published on the website
  • Semaglutide from $200/mo and tirzepatide from $250/mo
  • Lab panels included with clinician-supervised dosing
  • LegitScript certified clinic
  • Lead PA-C with over a decade in obesity medicine

Where it loses points

  • Telehealth limited to MO, IA, KS, UT, and WA
  • Compounded GLP-1 only, not brand-name
  • No insurance billing (cash-pay)
  • PA-led rather than MD/DO-led

Also worth a look

Neither is our top-graded pick — CoreAge Rx leads the scorecard

Across all 499 providers, CoreAge Rx grades highest at 91.8/100 (A−). Top of the scorecard: flat transparent pricing, both molecules, nationwide — no teaser-rate games.

Pricing/verification reflect each provider's public disclosures at last grading; the WeighScore is our editorial judgment per the methodology. Prices change — confirm on each provider's site. Not medical advice; see our disclosure.

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