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Head-to-head · WeighScore

Ascend Vitality vs Luma Meds

Ascend Vitality
Graded #307

Higher grade

vs+3.1000000000000014
Luma Meds
Graded #391

Lower grade

The verdict

Ascend Vitality takes it — 60.9/100 to 57.8/100.

Ascend Vitality grades higher on WeighScore, our editorial score across cost value, dose & formulation, clinical oversight, labs & monitoring, fulfillment and contract terms. Ascend Vitality is a cash-pay GLP-1 telehealth provider offering compounded semaglutide (starting at $199/mo) and compounded tirzepatide (starting at $299/mo) as both weekly injectables and needle-free…

We may earn a commission if you start care through some of these links, at no extra cost to you. It never moves the WeighScore, which is the weighted average of the six factors shown for every provider, and what we write about a provider is the same either way. See our disclosure.

Factor by factor

The same six graded dimensions, side by side. See the methodology.

Cost valueAscend Vitality +18
50
32
Dose & formulationAscend Vitality +11
75
64
Clinical oversightLuma Meds +16
74
90
Labs & monitoringLuma Meds +3
52
55
FulfillmentLuma Meds +11
65
76
Contract termsAscend Vitality +17
37
20
Ascend Vitality · left barLuma Meds · right bar

The numbers

MetricAscend VitalityLuma Meds
WeighScore60.9/10057.8/100
GradeCC
Scorecard rank#307#391
Semaglutide$199/mo (compounded)$249/mo (compounded)
Tirzepatide$299/mo (compounded)$299/mo (compounded)
CoverageCoverage not publishedCoverage not published
Brand-name accessCompounded onlyCompounded only
Oral / sublingualYesInjection only
Ascend Vitality

Graded #307 · C

Strengths

  • Both injectable and needle-free oral tablet forms of semaglutide and tirzepatide
  • LegitScript certified
  • Transparent cash-pay pricing with cancel-anytime subscription
  • Legal entity and address publicly disclosed (Ascend Vitality LLC, Sheridan, WY)

Where it loses points

  • All medications are compounded — FDA does not review compounded drugs for safety/effectiveness
  • No named compounding pharmacy partner disclosed
  • No public state-by-state availability list (homepage cites exclusions: LA, MS, KS, NM, WV)
  • Per-dose/titration pricing not published; only 'starting at' prices shown
Luma Meds

Graded #391 · C

Strengths

  • LegitScript certified — a credibility mark fewer compounded GLP-1 providers carry
  • Free discreet shipping and unlimited 24/7 support on every plan
  • Compounded semaglutide and tirzepatide from FDA-regulated 503A/503B pharmacies
  • '100,000+ members treated' claim with physician-supervised online care
  • 3-month bundle pricing brings semaglutide as low as $140/mo

Where it loses points

  • Compounding pharmacy partner not publicly named
  • States available not published
  • Monthly semaglutide ($249/mo) is above many lower-cost compounded competitors
  • No oral formulation options listed
  • Compounded medications are not FDA-approved

Also worth a look

Neither is our top-graded pick — CoreAge Rx leads the scorecard

Across all 499 providers, CoreAge Rx grades highest at 91.8/100 (A−). Top of the scorecard: flat transparent pricing, both molecules, nationwide — no teaser-rate games.

Pricing/verification reflect each provider's public disclosures at last grading; the WeighScore is our editorial judgment per the methodology. Prices change — confirm on each provider's site. Not medical advice; see our disclosure.

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