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Head-to-head · WeighScore

Ascend Vitality vs Loop Health

Ascend Vitality
Graded #307

Lower grade

vs+9.100000000000001
Loop Health
Graded #114

Higher grade

The verdict

Loop Health takes it — 70/100 to 60.9/100.

Loop Health grades higher on WeighScore, our editorial score across cost value, dose & formulation, clinical oversight, labs & monitoring, fulfillment and contract terms. Loop Health is a US telehealth membership platform offering compounded semaglutide and tirzepatide under its Loop Lean program, alongside peptides, NAD+, sermorelin, coaching, and bloodwork.

We may earn a commission if you start care through some of these links, at no extra cost to you. It never moves the WeighScore, which is the weighted average of the six factors shown for every provider, and what we write about a provider is the same either way. See our disclosure.

Factor by factor

The same six graded dimensions, side by side. See the methodology.

Cost valueLoop Health +29
50
79
Dose & formulationAscend Vitality +11
75
64
Clinical oversightLoop Health +5
74
79
Labs & monitoringLoop Health +21
52
73
FulfillmentAscend Vitality +3
65
62
Contract termsLoop Health +4
37
41
Ascend Vitality · left barLoop Health · right bar

The numbers

MetricAscend VitalityLoop Health
WeighScore60.9/10070/100
GradeCC
Scorecard rank#307#114
Semaglutide$199/mo (compounded)$79/mo (plus a separate fee, compounded)
Tirzepatide$299/mo (compounded)$125/mo (annual plan, plus a separate fee, compounded)
CoverageCoverage not publishedCoverage not published
Brand-name accessCompounded onlyCompounded only
Oral / sublingualYesInjection only
Ascend Vitality

Graded #307 · C

Strengths

  • Both injectable and needle-free oral tablet forms of semaglutide and tirzepatide
  • LegitScript certified
  • Transparent cash-pay pricing with cancel-anytime subscription
  • Legal entity and address publicly disclosed (Ascend Vitality LLC, Sheridan, WY)

Where it loses points

  • All medications are compounded — FDA does not review compounded drugs for safety/effectiveness
  • No named compounding pharmacy partner disclosed
  • No public state-by-state availability list (homepage cites exclusions: LA, MS, KS, NM, WV)
  • Per-dose/titration pricing not published; only 'starting at' prices shown
Loop Health

Graded #114 · C

Strengths

  • Multi-product wellness platform — GLP-1 plus peptides, NAD+, coaching, bloodwork
  • Low membership entry point ($79/mo)
  • Annual plan includes monthly 'research credit' toward compounds
  • Explicit compounded-drug FDA disclaimer on-site

Where it loses points

  • Per-dose GLP-1 drug pricing not transparent on public site (compounds billed separately by pharmacy)
  • States-served list not enumerated — only 'select U.S. states'
  • Platform explicitly 'is not a healthcare provider' — relies on independent provider network
  • No LegitScript number disclosed on homepage

Also worth a look

Neither is our top-graded pick — CoreAge Rx leads the scorecard

Across all 499 providers, CoreAge Rx grades highest at 91.8/100 (A−). Top of the scorecard: flat transparent pricing, both molecules, nationwide — no teaser-rate games.

Pricing/verification reflect each provider's public disclosures at last grading; the WeighScore is our editorial judgment per the methodology. Prices change — confirm on each provider's site. Not medical advice; see our disclosure.

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