Head-to-head · WeighScore
Ascend Vitality vs Joi + Blokes
The verdict
Joi + Blokes takes it — 66.1/100 to 60.9/100.
Joi + Blokes grades higher on WeighScore, our editorial score across cost value, dose & formulation, clinical oversight, labs & monitoring, fulfillment and contract terms. Joi + Blokes is a hormone-first telehealth platform with parallel programs for women (Joi) and men (Blokes), now expanded to compounded GLP-1s for weight loss.
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Factor by factor
The same six graded dimensions, side by side. See the methodology.
The numbers
| Metric | Ascend Vitality | Joi + Blokes |
|---|---|---|
| WeighScore | 60.9/100 | 66.1/100 |
| Grade | C | C |
| Scorecard rank | #307 | #203 |
| Semaglutide | $199/mo (compounded) | $199/mo (promotional rate, quarterly plan, compounded) |
| Tirzepatide | $299/mo (compounded) | $299/mo (quarterly plan, compounded) |
| Coverage | Coverage not published | Coverage not published |
| Brand-name access | Compounded only | Compounded only |
| Oral / sublingual | Yes | Injection only |
Graded #307 · C
Strengths
- Both injectable and needle-free oral tablet forms of semaglutide and tirzepatide
- LegitScript certified
- Transparent cash-pay pricing with cancel-anytime subscription
- Legal entity and address publicly disclosed (Ascend Vitality LLC, Sheridan, WY)
Where it loses points
- All medications are compounded — FDA does not review compounded drugs for safety/effectiveness
- No named compounding pharmacy partner disclosed
- No public state-by-state availability list (homepage cites exclusions: LA, MS, KS, NM, WV)
- Per-dose/titration pricing not published; only 'starting at' prices shown
Graded #203 · C
Strengths
- Separate programs for women (Joi) and men (Blokes) — most GLP-1 telehealth is gender-agnostic
- Trustpilot 4.6/5 from 1,254+ reviews — among the strongest review signals in the category
- Monthly price includes medication, dosing support, clinician consults, and health coaching
- Integrated hormone + GLP-1 programs help patients on testosterone or perimenopausal protocols
- First-month discount ($99 sema / $149 tirz) lowers the barrier to trying GLP-1s
Where it loses points
- Billed quarterly — a 3-month commitment up front, not month-to-month
- Different pricing in NY and NJ — verify your state's cost before committing
- Per-state availability isn't listed; it's zip-code gated behind signup
- Months 2+ cost more ($199 sema / $299 tirz) than the headline intro price
- No FDA-approved Wegovy — compounded only on the GLP-1 side; Zepbound carries a separate visit fee
Also worth a look
Neither is our top-graded pick — CoreAge Rx leads the scorecard
Across all 499 providers, CoreAge Rx grades highest at 91.8/100 (A−). Top of the scorecard: flat transparent pricing, both molecules, nationwide — no teaser-rate games.
Pricing/verification reflect each provider's public disclosures at last grading; the WeighScore is our editorial judgment per the methodology. Prices change — confirm on each provider's site. Not medical advice; see our disclosure.