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Head-to-head · WeighScore

Ascend Vitality vs Blis MD

Ascend Vitality
Graded #307

Lower grade

vs+11.800000000000004
Blis MD
Graded #74

Higher grade

The verdict

Blis MD takes it — 72.7/100 to 60.9/100.

Blis MD grades higher on WeighScore, our editorial score across cost value, dose & formulation, clinical oversight, labs & monitoring, fulfillment and contract terms. Blis MD is a US telehealth offering personalized GLP-1 weight-loss treatment with compounded semaglutide and tirzepatide, prescribed after a free virtual consultation with a licensed provider.

We may earn a commission if you start care through some of these links, at no extra cost to you. It never moves the WeighScore, which is the weighted average of the six factors shown for every provider, and what we write about a provider is the same either way. See our disclosure.

Factor by factor

The same six graded dimensions, side by side. See the methodology.

Cost valueBlis MD +38
50
88
Dose & formulationAscend Vitality +3
75
72
Clinical oversightEven
74
74
Labs & monitoringBlis MD +10
52
62
FulfillmentEven
65
65
Contract termsBlis MD +18
37
55
Ascend Vitality · left barBlis MD · right bar

The numbers

MetricAscend VitalityBlis MD
WeighScore60.9/10072.7/100
GradeCC
Scorecard rank#307#74
Semaglutide$199/mo (compounded)$139/mo
Tirzepatide$299/mo (compounded)$199/mo
CoverageCoverage not publishedCoverage not published
Brand-name accessCompounded onlyCompounded only
Oral / sublingualYesInjection only
Ascend Vitality

Graded #307 · C

Strengths

  • Both injectable and needle-free oral tablet forms of semaglutide and tirzepatide
  • LegitScript certified
  • Transparent cash-pay pricing with cancel-anytime subscription
  • Legal entity and address publicly disclosed (Ascend Vitality LLC, Sheridan, WY)

Where it loses points

  • All medications are compounded — FDA does not review compounded drugs for safety/effectiveness
  • No named compounding pharmacy partner disclosed
  • No public state-by-state availability list (homepage cites exclusions: LA, MS, KS, NM, WV)
  • Per-dose/titration pricing not published; only 'starting at' prices shown
Blis MD

Graded #74 · C

Strengths

  • Transparent flat monthly pricing published upfront (139 dollars semaglutide, 199 dollars tirzepatide)
  • Free initial virtual consultation with a licensed provider
  • Both semaglutide and tirzepatide offered with ongoing provider check-ins

Where it loses points

  • Compounding pharmacy is not named publicly
  • States served are not listed on the site
  • Thin public trust signals (no LegitScript seal or named medical director found)

Also worth a look

Neither is our top-graded pick — CoreAge Rx leads the scorecard

Across all 499 providers, CoreAge Rx grades highest at 91.8/100 (A−). Top of the scorecard: flat transparent pricing, both molecules, nationwide — no teaser-rate games.

Pricing/verification reflect each provider's public disclosures at last grading; the WeighScore is our editorial judgment per the methodology. Prices change — confirm on each provider's site. Not medical advice; see our disclosure.

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