Head-to-head · WeighScore
Ascend Vitality vs Avono Health
The verdict
Ascend Vitality takes it — 60.9/100 to 58.7/100.
Ascend Vitality grades higher on WeighScore, our editorial score across cost value, dose & formulation, clinical oversight, labs & monitoring, fulfillment and contract terms. Ascend Vitality is a cash-pay GLP-1 telehealth provider offering compounded semaglutide (starting at $199/mo) and compounded tirzepatide (starting at $299/mo) as both weekly injectables and needle-free…
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Factor by factor
The same six graded dimensions, side by side. See the methodology.
The numbers
| Metric | Ascend Vitality | Avono Health |
|---|---|---|
| WeighScore | 60.9/100 | 58.7/100 |
| Grade | C | C |
| Scorecard rank | #307 | #361 |
| Semaglutide | $199/mo (compounded) | $269/mo (compounded) |
| Tirzepatide | $299/mo (compounded) | $349/mo (compounded) |
| Coverage | Coverage not published | Coverage not published |
| Brand-name access | Compounded only | Compounded only |
| Oral / sublingual | Yes | Yes |
Graded #307 · C
Strengths
- Both injectable and needle-free oral tablet forms of semaglutide and tirzepatide
- LegitScript certified
- Transparent cash-pay pricing with cancel-anytime subscription
- Legal entity and address publicly disclosed (Ascend Vitality LLC, Sheridan, WY)
Where it loses points
- All medications are compounded — FDA does not review compounded drugs for safety/effectiveness
- No named compounding pharmacy partner disclosed
- No public state-by-state availability list (homepage cites exclusions: LA, MS, KS, NM, WV)
- Per-dose/titration pricing not published; only 'starting at' prices shown
Graded #361 · C
Strengths
- Transparent tiered pricing from $179/mo (microdose semaglutide injection)
- Full compounded range — semaglutide and tirzepatide, injection and oral, microdose and standard
- Free and discreet shipping; 24/7/365 messaging support; 100% online
- US-licensed clinicians and pharmacies; bundle discounts at 3/6/12 months
Where it loses points
- Medications are compounded, not FDA-approved brand-name
- Compounding pharmacy not publicly named
- State availability not published
- Newer brand with limited independent review history
Also worth a look
Neither is our top-graded pick — CoreAge Rx leads the scorecard
Across all 499 providers, CoreAge Rx grades highest at 91.8/100 (A−). Top of the scorecard: flat transparent pricing, both molecules, nationwide — no teaser-rate games.
Pricing/verification reflect each provider's public disclosures at last grading; the WeighScore is our editorial judgment per the methodology. Prices change — confirm on each provider's site. Not medical advice; see our disclosure.