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Head-to-head · WeighScore

Ascend Medical vs SkyRx

Ascend Medical
Graded #425

Lower grade

vs+3
SkyRx
Graded #355

Higher grade

The verdict

SkyRx takes it — 58.9/100 to 55.9/100.

SkyRx grades higher on WeighScore, our editorial score across cost value, dose & formulation, clinical oversight, labs & monitoring, fulfillment and contract terms. SkyRx (sky-rx.co) is a US telehealth weight-loss program offering compounded semaglutide as an injection or oral drops, with compounded tirzepatide listed as coming soon.

We may earn a commission if you start care through some of these links, at no extra cost to you. It never moves the WeighScore, which is the weighted average of the six factors shown for every provider, and what we write about a provider is the same either way. See our disclosure.

Factor by factor

The same six graded dimensions, side by side. See the methodology.

Cost valueSkyRx +11
45
56
Dose & formulationSkyRx +31
40
71
Clinical oversightAscend Medical +17
85
68
Labs & monitoringAscend Medical +10
62
52
FulfillmentSkyRx +5
59
64
Contract termsAscend Medical +21
41
20
Ascend Medical · left barSkyRx · right bar

The numbers

MetricAscend MedicalSkyRx
WeighScore55.9/10058.9/100
GradeCC
Scorecard rank#425#355
SemaglutideNot disclosed$199/mo (all doses, 12-month plan, compounded)
TirzepatideNot disclosedNot disclosed
Coverage2 statesCoverage not published
Brand-name accessCompounded onlyCompounded only
Oral / sublingualInjection onlyYes
Ascend Medical

Graded #425 · C

Strengths

  • Whole-person virtual primary care that includes a medical weight loss program
  • Staffed by licensed MDs, DOs, NPs and PAs
  • Integrates weight loss with primary, mental health and diabetes care
  • Clear state availability (Georgia and Texas)

Where it loses points

  • Available only in Georgia and Texas
  • Specific GLP-1 medications and branded-vs-compounded status not published
  • No pricing disclosed on public pages
  • Weight loss is one service among many, not a dedicated GLP-1 specialist
SkyRx

Graded #355 · C

Strengths

  • All-inclusive 199 dollars per month covers medication, supplies, doctor visit and shipping
  • Offers both injectable and oral semaglutide, dispensed by FDA-registered 503B pharmacies
  • Same-day shipping for orders before 2pm ET in temperature-controlled packaging

Where it loses points

  • 199 dollars pricing requires a 12-month subscription paid upfront
  • Tirzepatide only listed as coming soon
  • GLP-1s not yet available in all 50 states; specific states not listed

Also worth a look

Neither is our top-graded pick — CoreAge Rx leads the scorecard

Across all 499 providers, CoreAge Rx grades highest at 91.8/100 (A−). Top of the scorecard: flat transparent pricing, both molecules, nationwide — no teaser-rate games.

Pricing/verification reflect each provider's public disclosures at last grading; the WeighScore is our editorial judgment per the methodology. Prices change — confirm on each provider's site. Not medical advice; see our disclosure.

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