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Head-to-head · WeighScore

Ascend Medical vs Onyx Weight Loss

Ascend Medical
Graded #425

Lower grade

vs+2.8999999999999986
Onyx Weight Loss
Graded #359

Higher grade

The verdict

Onyx Weight Loss takes it — 58.8/100 to 55.9/100.

Onyx Weight Loss grades higher on WeighScore, our editorial score across cost value, dose & formulation, clinical oversight, labs & monitoring, fulfillment and contract terms. Onyx Weight Loss is a nurse-practitioner-led telehealth clinic based in Mooresville, NC, offering GLP-1 and GLP-1/GIP weight-loss medications alongside peptides and HRT across 8 states.

We may earn a commission if you start care through some of these links, at no extra cost to you. It never moves the WeighScore, which is the weighted average of the six factors shown for every provider, and what we write about a provider is the same either way. See our disclosure.

Factor by factor

The same six graded dimensions, side by side. See the methodology.

Cost valueAscend Medical +2
45
43
Dose & formulationOnyx Weight Loss +24
40
64
Clinical oversightAscend Medical +10
85
75
Labs & monitoringOnyx Weight Loss +1
62
63
FulfillmentAscend Medical +6
59
53
Contract termsOnyx Weight Loss +14
41
55
Ascend Medical · left barOnyx Weight Loss · right bar

The numbers

MetricAscend MedicalOnyx Weight Loss
WeighScore55.9/10058.8/100
GradeCC
Scorecard rank#425#359
SemaglutideNot disclosed$228/mo (starting dose, compounded)
TirzepatideNot disclosed$280/mo (starting dose, compounded)
Coverage2 states8 states
Brand-name accessCompounded onlyCompounded only
Oral / sublingualInjection onlyInjection only
Ascend Medical

Graded #425 · C

Strengths

  • Whole-person virtual primary care that includes a medical weight loss program
  • Staffed by licensed MDs, DOs, NPs and PAs
  • Integrates weight loss with primary, mental health and diabetes care
  • Clear state availability (Georgia and Texas)

Where it loses points

  • Available only in Georgia and Texas
  • Specific GLP-1 medications and branded-vs-compounded status not published
  • No pricing disclosed on public pages
  • Weight loss is one service among many, not a dedicated GLP-1 specialist
Onyx Weight Loss

Graded #359 · C

Strengths

  • Competitive entry pricing: semaglutide from $228/mo and tirzepatide from $280/mo with medication + supplies included
  • Nurse-practitioner-led care: founder Tasha Vangile FNP-C (20+ years) and Stephanie Robison APRN-CNP (27 years experience)
  • Low-cost $99/mo GLP-1 microdosing option for patients who prefer a gradual titration start
  • Strive Pharmacy partnership implies compounded 503A-quality supply chain from a known pharmacy
  • Multi-modal clinic: GLP-1 + peptides + HRT + nutrition coaching available under one provider team

Where it loses points

  • Only 8 states (NC, CO, ME, VT, VA, IA, NH, PA) — excludes the majority of the US
  • No LegitScript certification; credentialing evidence limited to local 2025 Best of Iredell award
  • Specific drug names (semaglutide/tirzepatide) never stated on website; compounded status inferred, not disclosed
  • Labs not included or mentioned; no baseline bloodwork protocol published
  • Pricing shown as 'Starting at' with no dose-escalation tier pricing disclosed publicly

Also worth a look

Neither is our top-graded pick — CoreAge Rx leads the scorecard

Across all 499 providers, CoreAge Rx grades highest at 91.8/100 (A−). Top of the scorecard: flat transparent pricing, both molecules, nationwide — no teaser-rate games.

Pricing/verification reflect each provider's public disclosures at last grading; the WeighScore is our editorial judgment per the methodology. Prices change — confirm on each provider's site. Not medical advice; see our disclosure.

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