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Head-to-head · WeighScore

Ascend Medical vs MediRX

Ascend Medical
Graded #425

Lower grade

vs+10.199999999999996
MediRX
Graded #206

Higher grade

The verdict

MediRX takes it — 66.1/100 to 55.9/100.

MediRX grades higher on WeighScore, our editorial score across cost value, dose & formulation, clinical oversight, labs & monitoring, fulfillment and contract terms. MediRX is a telehealth weight-loss platform offering compounded GLP-1 injections — semaglutide starting at $149/month and tirzepatide starting at $199/month — plus NAD+ and a name-brand GLP-1 option.

We may earn a commission if you start care through some of these links, at no extra cost to you. It never moves the WeighScore, which is the weighted average of the six factors shown for every provider, and what we write about a provider is the same either way. See our disclosure.

Factor by factor

The same six graded dimensions, side by side. See the methodology.

Cost valueMediRX +19
45
64
Dose & formulationMediRX +37
40
77
Clinical oversightAscend Medical +3
85
82
Labs & monitoringAscend Medical +9
62
53
FulfillmentMediRX +14
59
73
Contract termsAscend Medical +21
41
20
Ascend Medical · left barMediRX · right bar

The numbers

MetricAscend MedicalMediRX
WeighScore55.9/10066.1/100
GradeCC
Scorecard rank#425#206
SemaglutideNot disclosed$149/mo (compounded)
TirzepatideNot disclosed$199/mo (compounded)
Coverage2 statesCoverage not published
Brand-name accessCompounded onlyYes
Oral / sublingualInjection onlyInjection only
Ascend Medical

Graded #425 · C

Strengths

  • Whole-person virtual primary care that includes a medical weight loss program
  • Staffed by licensed MDs, DOs, NPs and PAs
  • Integrates weight loss with primary, mental health and diabetes care
  • Clear state availability (Georgia and Texas)

Where it loses points

  • Available only in Georgia and Texas
  • Specific GLP-1 medications and branded-vs-compounded status not published
  • No pricing disclosed on public pages
  • Weight loss is one service among many, not a dedicated GLP-1 specialist
MediRX

Graded #206 · C

Strengths

  • LegitScript Certified — a meaningful trust signal for an online pharmacy
  • Named operating entity disclosed (MediRX, Inc., Wyoming)
  • Care and pharmacy fulfillment run on OpenLoop Health's licensed network
  • Low promotional first-month pricing — semaglutide first month as low as $70

Where it loses points

  • Doesn't publish the exact states it serves; telehealth rules vary by state
  • Ongoing monthly price rises after the promotional first month
  • Compounded semaglutide and tirzepatide injections — limited oral options
  • Specific compounding pharmacies aren't named beyond the OpenLoop network

Also worth a look

Neither is our top-graded pick — CoreAge Rx leads the scorecard

Across all 499 providers, CoreAge Rx grades highest at 91.8/100 (A−). Top of the scorecard: flat transparent pricing, both molecules, nationwide — no teaser-rate games.

Pricing/verification reflect each provider's public disclosures at last grading; the WeighScore is our editorial judgment per the methodology. Prices change — confirm on each provider's site. Not medical advice; see our disclosure.

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