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Head-to-head · WeighScore

Ascend Medical vs Jyra Health

Ascend Medical
Graded #425

Lower grade

vs+13.699999999999996
Jyra Health
Graded #117

Higher grade

The verdict

Jyra Health takes it — 69.6/100 to 55.9/100.

Jyra Health grades higher on WeighScore, our editorial score across cost value, dose & formulation, clinical oversight, labs & monitoring, fulfillment and contract terms. Jyra Health is an online weight-loss and longevity telehealth clinic offering compounded GLP-1 — semaglutide from $99/mo and tirzepatide from $133/mo (limited time) — prescribed by board-certified providers…

We may earn a commission if you start care through some of these links, at no extra cost to you. It never moves the WeighScore, which is the weighted average of the six factors shown for every provider, and what we write about a provider is the same either way. See our disclosure.

Factor by factor

The same six graded dimensions, side by side. See the methodology.

Cost valueJyra Health +27
45
72
Dose & formulationJyra Health +24
40
64
Clinical oversightAscend Medical +3
85
82
Labs & monitoringAscend Medical +9
62
53
FulfillmentJyra Health +29
59
88
Contract termsJyra Health +8
41
49
Ascend Medical · left barJyra Health · right bar

The numbers

MetricAscend MedicalJyra Health
WeighScore55.9/10069.6/100
GradeCC
Scorecard rank#425#117
SemaglutideNot disclosed$99/mo (starting dose, plus a separate fee, compounded)
TirzepatideNot disclosed$133/mo (starting dose, promotional rate, compounded)
Coverage2 statesAll 50 states
Brand-name accessCompounded onlyCompounded only
Oral / sublingualInjection onlyInjection only
Ascend Medical

Graded #425 · C

Strengths

  • Whole-person virtual primary care that includes a medical weight loss program
  • Staffed by licensed MDs, DOs, NPs and PAs
  • Integrates weight loss with primary, mental health and diabetes care
  • Clear state availability (Georgia and Texas)

Where it loses points

  • Available only in Georgia and Texas
  • Specific GLP-1 medications and branded-vs-compounded status not published
  • No pricing disclosed on public pages
  • Weight loss is one service among many, not a dedicated GLP-1 specialist
Jyra Health

Graded #117 · C

Strengths

  • Among the lowest compounded pricing — semaglutide from $99/mo and tirzepatide from $133/mo, with no membership and no hidden fees
  • Board-certified providers in all 50 states; no insurance required and free express delivery
  • Offers both compounded semaglutide and tirzepatide, plus a longevity track
  • Full legal suite published (Privacy, Terms, HIPAA, Refunds & Cancellations)

Where it loses points

  • The $133/mo tirzepatide price is flagged 'limited time' — verify current pricing before enrolling
  • Compounded medications are not FDA-approved (the site discloses this) — not brand Wegovy, Zepbound, Ozempic, or Mounjaro
  • Displays a self-hosted LegitScript badge but no verifiable seal or listing
  • Compounding pharmacy not named; appears to be a newer, smaller clinic (~300 patients/month)

Also worth a look

Neither is our top-graded pick — CoreAge Rx leads the scorecard

Across all 499 providers, CoreAge Rx grades highest at 91.8/100 (A−). Top of the scorecard: flat transparent pricing, both molecules, nationwide — no teaser-rate games.

Pricing/verification reflect each provider's public disclosures at last grading; the WeighScore is our editorial judgment per the methodology. Prices change — confirm on each provider's site. Not medical advice; see our disclosure.

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