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Head-to-head · WeighScore

ARSYNL Rx vs Sesame Care

ARSYNL Rx
Graded #348

Lower grade

vs+28.699999999999996
Sesame Care
Graded #2

Higher grade

The verdict

Sesame Care takes it — 87.8/100 to 59.1/100.

Sesame Care grades higher on WeighScore, our editorial score across cost value, dose & formulation, clinical oversight, labs & monitoring, fulfillment and contract terms. An established national telehealth marketplace with the widest real brand-name GLP-1 access on the board — Wegovy (pen and pill), Zepbound, Ozempic and Mounjaro — plus provider-by-provider price transparency.

We may earn a commission if you start care through some of these links, at no extra cost to you. It never moves the WeighScore, which is the weighted average of the six factors shown for every provider, and what we write about a provider is the same either way. See our disclosure.

Factor by factor

The same six graded dimensions, side by side. See the methodology.

Cost valueSesame Care +41
43
84
Dose & formulationSesame Care +28
64
92
Clinical oversightSesame Care +16
78
94
Labs & monitoringSesame Care +31
53
84
FulfillmentSesame Care +17
63
80
Contract termsSesame Care +37
55
92
ARSYNL Rx · left barSesame Care · right bar

The numbers

MetricARSYNL RxSesame Care
WeighScore59.1/10087.8/100
GradeCB+
Scorecard rank#348#2
Semaglutide$233/mo (compounded)From $149/mo (brand Wegovy pill)
Tirzepatide$366/mo (compounded)Brand Zepbound (price varies)
CoverageCoverage not publishedNationwide marketplace
Brand-name accessCompounded onlyYes
Oral / sublingualInjection onlyYes
ARSYNL Rx

Graded #348 · C

Strengths

  • Offers compounded semaglutide and tirzepatide, including a needle-free tirzepatide hypospray option
  • Veteran-founded telehealth with clinician-prescribed, personalized treatment
  • Multi-service platform — also covers hair restoration, TRT, sexual health, and longevity
  • Medications shipped discreetly to your home

Where it loses points

  • Pricing is not shown until you select a product (product pages sit behind a bot-verification gate)
  • Compounded GLP-1s are not FDA-approved finished products
  • Compounding pharmacy partner and exact state coverage are not disclosed on the site
  • No LegitScript certification visible on the accessible pages
Sesame Care

Graded #2 · B+

Strengths

  • Real FDA-approved brand-name access — Wegovy pen and pill, Zepbound, Ozempic, Mounjaro and Rybelsus
  • Established platform (operating since 2018) with LegitScript, BBB accreditation and large third-party review volume
  • You choose the provider and see the price up front — genuine marketplace transparency
  • Oral routes available (Wegovy pill, Rybelsus)

Where it loses points

  • A generalist marketplace, not a dedicated weight-loss program — lighter ongoing hand-holding than a specialist desk
  • Two-part cost (a platform subscription plus the medication) makes the true monthly total harder to compare
  • Brand-name cash prices can run high without insurance

Also worth a look

Neither is our top-graded pick — CoreAge Rx leads the scorecard

Across all 499 providers, CoreAge Rx grades highest at 91.8/100 (A−). Top of the scorecard: flat transparent pricing, both molecules, nationwide — no teaser-rate games.

Pricing/verification reflect each provider's public disclosures at last grading; the WeighScore is our editorial judgment per the methodology. Prices change — confirm on each provider's site. Not medical advice; see our disclosure.

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