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Head-to-head · WeighScore

ARSYNL Rx vs Cielo

ARSYNL Rx
Graded #348

Lower grade

vs+10.300000000000004
Cielo
Graded #127

Higher grade

The verdict

Cielo takes it — 69.4/100 to 59.1/100.

Cielo grades higher on WeighScore, our editorial score across cost value, dose & formulation, clinical oversight, labs & monitoring, fulfillment and contract terms. Cielo is a compounded-GLP-1-only telehealth platform offering semaglutide and tirzepatide with no brand-name drugs and no TRT, hair, or mental-health add-ons — a focused, single-purpose alternative to…

We may earn a commission if you start care through some of these links, at no extra cost to you. It never moves the WeighScore, which is the weighted average of the six factors shown for every provider, and what we write about a provider is the same either way. See our disclosure.

Factor by factor

The same six graded dimensions, side by side. See the methodology.

Cost valueCielo +33
43
76
Dose & formulationCielo +21
64
85
Clinical oversightCielo +1
78
79
Labs & monitoringEven
53
53
FulfillmentCielo +4
63
67
Contract termsARSYNL Rx +35
55
20
ARSYNL Rx · left barCielo · right bar

The numbers

MetricARSYNL RxCielo
WeighScore59.1/10069.4/100
GradeCC
Scorecard rank#348#127
Semaglutide$233/mo (compounded)$149/mo (all doses, compounded)
Tirzepatide$366/mo (compounded)$249/mo (all doses, compounded)
CoverageCoverage not publishedCoverage not published
Brand-name accessCompounded onlyYes
Oral / sublingualInjection onlyInjection only
ARSYNL Rx

Graded #348 · C

Strengths

  • Offers compounded semaglutide and tirzepatide, including a needle-free tirzepatide hypospray option
  • Veteran-founded telehealth with clinician-prescribed, personalized treatment
  • Multi-service platform — also covers hair restoration, TRT, sexual health, and longevity
  • Medications shipped discreetly to your home

Where it loses points

  • Pricing is not shown until you select a product (product pages sit behind a bot-verification gate)
  • Compounded GLP-1s are not FDA-approved finished products
  • Compounding pharmacy partner and exact state coverage are not disclosed on the site
  • No LegitScript certification visible on the accessible pages
Cielo

Graded #127 · C

Strengths

  • Among the lowest 3-month bundle prices in compounded GLP-1 ($115/mo semaglutide)
  • Single flat price across all doses simplifies titration planning
  • Corporate address (St. Petersburg, FL) and customer-service phone published

Where it loses points

  • No LegitScript, NABP .pharmacy, or HIPAA badge on the home page
  • Pharmacy partner not named (only 'regulated FDA pharmacy partners')
  • State coverage list not published — can't verify all-50-state availability
  • Clinical care runs through MD Integrations, a shared third-party network used by many brands
  • No brand-name Wegovy or Zepbound option

Also worth a look

Neither is our top-graded pick — CoreAge Rx leads the scorecard

Across all 499 providers, CoreAge Rx grades highest at 91.8/100 (A−). Top of the scorecard: flat transparent pricing, both molecules, nationwide — no teaser-rate games.

Pricing/verification reflect each provider's public disclosures at last grading; the WeighScore is our editorial judgment per the methodology. Prices change — confirm on each provider's site. Not medical advice; see our disclosure.

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