Head-to-head · WeighScore
Arc-1 vs Trimrose
The verdict
Arc-1 takes it — 56.3/100 to 55.2/100, but only just.
Arc-1 grades higher on WeighScore, our editorial score across cost value, dose & formulation, clinical oversight, labs & monitoring, fulfillment and contract terms. Arc-1 offers compounded semaglutide (from $249.99) and compounded tirzepatide (from $299.99) as per-dose purchases, not monthly subscriptions. Trimrose is close behind and may still be the better fit — see the factor split below.
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Factor by factor
The same six graded dimensions, side by side. See the methodology.
The numbers
| Metric | Arc-1 | Trimrose |
|---|---|---|
| WeighScore | 56.3/100 | 55.2/100 |
| Grade | C | C |
| Scorecard rank | #417 | #446 |
| Semaglutide | $200/mo (0.5 mg dose, compounded) | Not disclosed |
| Tirzepatide | $200/mo (2.5 mg dose, compounded) | Not disclosed |
| Coverage | Coverage not published | Coverage not published |
| Brand-name access | Compounded only | Yes |
| Oral / sublingual | Injection only | Yes |
Graded #417 · C
Strengths
- Both compounded semaglutide and tirzepatide available
- Per-dose purchasing — no subscription or membership required
- 25% off plus free shipping promotion
- Broader longevity formulary (rapamycin, NAD+, sermorelin)
- LegitScript Certified badge now displayed on product pages
Where it loses points
- No legal entity name or address disclosed
- State availability not disclosed
- No named clinicians or pharmacy partners
- Per-dose pricing still climbs with dose (semaglutide 2.5mg is $549.99/mo, tirzepatide 7.5mg $399.99/mo)
Graded #446 · C
Strengths
- Free, no-cost, no-obligation online eligibility quiz before any commitment
- Offers a choice of a weekly compounded GLP-1 injection or a daily oral option
- Fully online — assessment, provider review, and home delivery with ongoing support
Where it loses points
- Runs on the CareValidate white-label platform and isn't the medical provider itself — a support@carevalidate.com address is exposed on the site
- Pricing isn't shown publicly; the cost and the specific compounded molecule appear only after you complete the eligibility quiz
- The states served, pharmacy partner and any LegitScript/503A certification aren't disclosed on the public site
- Markets 'up to 22.5% of body weight' — a trial figure for branded tirzepatide, not a guaranteed or compounded-specific outcome
- Compounded GLP-1s are not FDA-reviewed or approved — a different evidence and regulatory tier than brand-name
Also worth a look
Neither is our top-graded pick — CoreAge Rx leads the scorecard
Across all 499 providers, CoreAge Rx grades highest at 91.8/100 (A−). Top of the scorecard: flat transparent pricing, both molecules, nationwide — no teaser-rate games.
Pricing/verification reflect each provider's public disclosures at last grading; the WeighScore is our editorial judgment per the methodology. Prices change — confirm on each provider's site. Not medical advice; see our disclosure.