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Head-to-head · WeighScore

Arc-1 vs PCOS Sisters

Arc-1
Graded #416

Lower grade

vs+9.400000000000006
PCOS Sisters
Graded #219

Higher grade

The verdict

PCOS Sisters takes it — 65.7/100 to 56.3/100.

PCOS Sisters grades higher on WeighScore, our editorial score across cost value, dose & formulation, clinical oversight, labs & monitoring, fulfillment and contract terms. PCOS Sisters is a women's telehealth clinic focused on polycystic ovary syndrome that offers a GLP-1 weight and metabolic management program for 150 dollars per month with membership required.

We may earn a commission if you start care through some of these links, at no extra cost to you. It never moves the WeighScore, which is the weighted average of the six factors shown for every provider, and what we write about a provider is the same either way. See our disclosure.

Factor by factor

The same six graded dimensions, side by side. See the methodology.

Cost valuePCOS Sisters +17
44
61
Dose & formulationPCOS Sisters +34
54
88
Clinical oversightArc-1 +2
72
70
Labs & monitoringEven
52
52
FulfillmentPCOS Sisters +3
62
65
Contract termsArc-1 +20
61
41
Arc-1 · left barPCOS Sisters · right bar

The numbers

MetricArc-1PCOS Sisters
WeighScore56.3/10065.7/100
GradeCC
Scorecard rank#416#219
Semaglutide$200/mo (0.5 mg dose, compounded)$150/mo (plus a separate fee, compounded)
Tirzepatide$200/mo (2.5 mg dose, compounded)$150/mo (plus a separate fee, compounded)
CoverageCoverage not published12 states
Brand-name accessCompounded onlyYes
Oral / sublingualInjection onlyYes
Arc-1

Graded #416 · C

Strengths

  • Both compounded semaglutide and tirzepatide available
  • Per-dose purchasing — no subscription or membership required
  • 25% off plus free shipping promotion
  • Broader longevity formulary (rapamycin, NAD+, sermorelin)
  • LegitScript Certified badge now displayed on product pages

Where it loses points

  • No legal entity name or address disclosed
  • State availability not disclosed
  • No named clinicians or pharmacy partners
  • Per-dose pricing still climbs with dose (semaglutide 2.5mg is $549.99/mo, tirzepatide 7.5mg $399.99/mo)
PCOS Sisters

Graded #219 · C

Strengths

  • Dedicated PCOS specialty model with metabolic program and fitness app included
  • Transparent 150 dollars per month GLP-1 management fee
  • Names real partner pharmacies (Strive, Striker) and lists phone support

Where it loses points

  • Only 12 states served
  • Membership required on top of the medical program
  • Unclear whether pharmacy dispensing fees are separate from the 150/mo fee

Also worth a look

Neither is our top-graded pick — CoreAge Rx leads the scorecard

Across all 499 providers, CoreAge Rx grades highest at 91.8/100 (A−). Top of the scorecard: flat transparent pricing, both molecules, nationwide — no teaser-rate games.

Pricing/verification reflect each provider's public disclosures at last grading; the WeighScore is our editorial judgment per the methodology. Prices change — confirm on each provider's site. Not medical advice; see our disclosure.

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