Head-to-head · WeighScore
Arc-1 vs MediRX
The verdict
MediRX takes it — 66.1/100 to 56.3/100.
MediRX grades higher on WeighScore, our editorial score across cost value, dose & formulation, clinical oversight, labs & monitoring, fulfillment and contract terms. MediRX is a telehealth weight-loss platform offering compounded GLP-1 injections — semaglutide starting at $149/month and tirzepatide starting at $199/month — plus NAD+ and a name-brand GLP-1 option.
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Factor by factor
The same six graded dimensions, side by side. See the methodology.
The numbers
| Metric | Arc-1 | MediRX |
|---|---|---|
| WeighScore | 56.3/100 | 66.1/100 |
| Grade | C | C |
| Scorecard rank | #416 | #206 |
| Semaglutide | $200/mo (0.5 mg dose, compounded) | $149/mo (compounded) |
| Tirzepatide | $200/mo (2.5 mg dose, compounded) | $199/mo (compounded) |
| Coverage | Coverage not published | Coverage not published |
| Brand-name access | Compounded only | Yes |
| Oral / sublingual | Injection only | Injection only |
Graded #416 · C
Strengths
- Both compounded semaglutide and tirzepatide available
- Per-dose purchasing — no subscription or membership required
- 25% off plus free shipping promotion
- Broader longevity formulary (rapamycin, NAD+, sermorelin)
- LegitScript Certified badge now displayed on product pages
Where it loses points
- No legal entity name or address disclosed
- State availability not disclosed
- No named clinicians or pharmacy partners
- Per-dose pricing still climbs with dose (semaglutide 2.5mg is $549.99/mo, tirzepatide 7.5mg $399.99/mo)
Graded #206 · C
Strengths
- LegitScript Certified — a meaningful trust signal for an online pharmacy
- Named operating entity disclosed (MediRX, Inc., Wyoming)
- Care and pharmacy fulfillment run on OpenLoop Health's licensed network
- Low promotional first-month pricing — semaglutide first month as low as $70
Where it loses points
- Doesn't publish the exact states it serves; telehealth rules vary by state
- Ongoing monthly price rises after the promotional first month
- Compounded semaglutide and tirzepatide injections — limited oral options
- Specific compounding pharmacies aren't named beyond the OpenLoop network
Also worth a look
Neither is our top-graded pick — CoreAge Rx leads the scorecard
Across all 499 providers, CoreAge Rx grades highest at 91.8/100 (A−). Top of the scorecard: flat transparent pricing, both molecules, nationwide — no teaser-rate games.
Pricing/verification reflect each provider's public disclosures at last grading; the WeighScore is our editorial judgment per the methodology. Prices change — confirm on each provider's site. Not medical advice; see our disclosure.