Head-to-head · WeighScore
Arc-1 vs LillyDirect Foundayo
The verdict
LillyDirect Foundayo takes it — 67.2/100 to 56.3/100.
LillyDirect Foundayo grades higher on WeighScore, our editorial score across cost value, dose & formulation, clinical oversight, labs & monitoring, fulfillment and contract terms. Eli Lilly's manufacturer direct-pay channel for Foundayo (orforglipron), the first oral GLP-1 pill for weight loss.
We may earn a commission if you start care through some of these links, at no extra cost to you. It never moves the WeighScore, which is the weighted average of the six factors shown for every provider, and what we write about a provider is the same either way. See our disclosure.
Factor by factor
The same six graded dimensions, side by side. See the methodology.
The numbers
| Metric | Arc-1 | LillyDirect Foundayo |
|---|---|---|
| WeighScore | 56.3/100 | 67.2/100 |
| Grade | C | C |
| Scorecard rank | #416 | #165 |
| Semaglutide | $200/mo (0.5 mg dose, compounded) | Not disclosed |
| Tirzepatide | $200/mo (2.5 mg dose, compounded) | Not disclosed |
| Coverage | Coverage not published | All 50 states |
| Brand-name access | Compounded only | Yes |
| Oral / sublingual | Injection only | Yes |
Graded #416 · C
Strengths
- Both compounded semaglutide and tirzepatide available
- Per-dose purchasing — no subscription or membership required
- 25% off plus free shipping promotion
- Broader longevity formulary (rapamycin, NAD+, sermorelin)
- LegitScript Certified badge now displayed on product pages
Where it loses points
- No legal entity name or address disclosed
- State availability not disclosed
- No named clinicians or pharmacy partners
- Per-dose pricing still climbs with dose (semaglutide 2.5mg is $549.99/mo, tirzepatide 7.5mg $399.99/mo)
Graded #165 · C
Strengths
- Cheapest legal path to a brand-name GLP-1 in 2026 ($25/mo with savings card for commercial insurance)
- Direct from manufacturer — no compounding, no third-party reseller
- Daily oral pill, no injections, no refrigeration
- Available in all 50 states
Where it loses points
- Lower mean weight loss vs Wegovy (14.9%) and Zepbound (20.9%) — labeled-dose 11.1% per Foundayo PI
- Requires existing prescription from a separate prescriber (LillyDirect does not write the prescription)
- $25 savings card requires commercial insurance — Medicare and Medicaid not eligible
- Strict empty-stomach 30-minute window may be hard for some patients to follow
Also worth a look
Neither is our top-graded pick — CoreAge Rx leads the scorecard
Across all 499 providers, CoreAge Rx grades highest at 91.8/100 (A−). Top of the scorecard: flat transparent pricing, both molecules, nationwide — no teaser-rate games.
Pricing/verification reflect each provider's public disclosures at last grading; the WeighScore is our editorial judgment per the methodology. Prices change — confirm on each provider's site. Not medical advice; see our disclosure.