Head-to-head · WeighScore
Arc-1 vs Defy Medical
The verdict
Defy Medical takes it — 60.2/100 to 56.3/100.
Defy Medical grades higher on WeighScore, our editorial score across cost value, dose & formulation, clinical oversight, labs & monitoring, fulfillment and contract terms. Defy Medical is a long-running telehealth clinic, best known for hormone replacement, that also prescribes GLP-1 medications for weight loss.
We may earn a commission if you start care through some of these links, at no extra cost to you. It never moves the WeighScore, which is the weighted average of the six factors shown for every provider, and what we write about a provider is the same either way. See our disclosure.
Factor by factor
The same six graded dimensions, side by side. See the methodology.
The numbers
| Metric | Arc-1 | Defy Medical |
|---|---|---|
| WeighScore | 56.3/100 | 60.2/100 |
| Grade | C | C |
| Scorecard rank | #417 | #326 |
| Semaglutide | $200/mo (0.5 mg dose, compounded) | Not disclosed |
| Tirzepatide | $200/mo (2.5 mg dose, compounded) | Not disclosed |
| Coverage | Coverage not published | Coverage not published |
| Brand-name access | Compounded only | Compounded only |
| Oral / sublingual | Injection only | Yes |
Graded #417 · C
Strengths
- Both compounded semaglutide and tirzepatide available
- Per-dose purchasing — no subscription or membership required
- 25% off plus free shipping promotion
- Broader longevity formulary (rapamycin, NAD+, sermorelin)
- LegitScript Certified badge now displayed on product pages
Where it loses points
- No legal entity name or address disclosed
- State availability not disclosed
- No named clinicians or pharmacy partners
- Per-dose pricing still climbs with dose (semaglutide 2.5mg is $549.99/mo, tirzepatide 7.5mg $399.99/mo)
Graded #326 · C
Strengths
- Multiple GLP-1 options: semaglutide, tirzepatide, liraglutide
- Offers injection, ODT, and oral drop delivery forms
- Comprehensive blood testing and named medical director
- Established clinic with strong Trustpilot review volume
Where it loses points
- GLP-1 pricing not published on the website
- States served and shipping limits not disclosed
- Compounded versus brand status not stated online
- Lab-heavy, consult-first model may cost more upfront
Also worth a look
Neither is our top-graded pick — CoreAge Rx leads the scorecard
Across all 499 providers, CoreAge Rx grades highest at 91.8/100 (A−). Top of the scorecard: flat transparent pricing, both molecules, nationwide — no teaser-rate games.
Pricing/verification reflect each provider's public disclosures at last grading; the WeighScore is our editorial judgment per the methodology. Prices change — confirm on each provider's site. Not medical advice; see our disclosure.