Head-to-head · WeighScore
AquaVita NextGen vs Defy Medical
The verdict
Defy Medical takes it — 60.2/100 to 56.3/100.
Defy Medical grades higher on WeighScore, our editorial score across cost value, dose & formulation, clinical oversight, labs & monitoring, fulfillment and contract terms. Defy Medical is a long-running telehealth clinic, best known for hormone replacement, that also prescribes GLP-1 medications for weight loss.
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Factor by factor
The same six graded dimensions, side by side. See the methodology.
The numbers
| Metric | AquaVita NextGen | Defy Medical |
|---|---|---|
| WeighScore | 56.3/100 | 60.2/100 |
| Grade | C | C |
| Scorecard rank | #416 | #326 |
| Semaglutide | $375/mo (first-month rate, compounded) | Not disclosed |
| Tirzepatide | $320/mo (starting dose, 3-month plan, compounded) | Not disclosed |
| Coverage | 5 states | Coverage not published |
| Brand-name access | Compounded only | Compounded only |
| Oral / sublingual | Yes | Yes |
Graded #416 · C
Strengths
- Physical address in Lake Forest CA
- Named medical director (Dr. Steve Groke)
- Both semaglutide and tirzepatide including ODT tablets
- Compounding disclaimer present on site
Where it loses points
- Only 5 states (AZ, CA, FL, TX, NV)
- No LegitScript or PCAB accreditation
- Primarily a local medspa expanding into telehealth
- Only a first-month semaglutide price ($375, originally $499) is published; ongoing monthly price and all tirzepatide pricing remain unpublished
Graded #326 · C
Strengths
- Multiple GLP-1 options: semaglutide, tirzepatide, liraglutide
- Offers injection, ODT, and oral drop delivery forms
- Comprehensive blood testing and named medical director
- Established clinic with strong Trustpilot review volume
Where it loses points
- GLP-1 pricing not published on the website
- States served and shipping limits not disclosed
- Compounded versus brand status not stated online
- Lab-heavy, consult-first model may cost more upfront
Also worth a look
Neither is our top-graded pick — CoreAge Rx leads the scorecard
Across all 499 providers, CoreAge Rx grades highest at 91.8/100 (A−). Top of the scorecard: flat transparent pricing, both molecules, nationwide — no teaser-rate games.
Pricing/verification reflect each provider's public disclosures at last grading; the WeighScore is our editorial judgment per the methodology. Prices change — confirm on each provider's site. Not medical advice; see our disclosure.