Head-to-head · WeighScore
Amazon One Medical vs SynergenX Health
The verdict
Amazon One Medical takes it — 77.5/100 to 58.4/100.
Amazon One Medical grades higher on WeighScore, our editorial score across cost value, dose & formulation, clinical oversight, labs & monitoring, fulfillment and contract terms. Amazon One Medical is the unified Amazon GLP-1 channel — One Medical clinicians prescribe FDA-approved Wegovy, Zepbound, and Foundayo (no compounded products), and Amazon Pharmacy fulfills with same-day…
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Factor by factor
The same six graded dimensions, side by side. See the methodology.
The numbers
| Metric | Amazon One Medical | SynergenX Health |
|---|---|---|
| WeighScore | 77.5/100 | 58.4/100 |
| Grade | C+ | C |
| Scorecard rank | #45 | #374 |
| Semaglutide | Not disclosed | $150/mo (starting dose, plus a separate fee, compounded) |
| Tirzepatide | Not disclosed | Not disclosed |
| Coverage | All 50 states | 10 states |
| Brand-name access | Yes | Compounded only |
| Oral / sublingual | Injection only | Injection only |
Graded #45 · C+
Strengths
- As low as $1/day ($25/month) for brand-name Foundayo with insurance and the auto-applied Lilly coupon
- Same-day delivery in nearly 3,000 US cities at launch, expanding to 4,500 by end of 2026
- In-office pharmacist kiosks at select One Medical clinics let you walk out with Foundayo in hand
- Cash-pay $5/day ($149/month) is competitive for the same FDA-approved brand-name product
- Real-time availability, transparent pricing, and automatic manufacturer coupon at checkout
Where it loses points
- Headline $25/month needs both insurance and the Lilly Savings Card — uninsured pay $149/month
- Same-day delivery is geographically gated; outside major cities it drops to next-day or slower
- Pricing is set by manufacturer savings programs and can change at any time
- No compounded options — brand-name only (Foundayo, Wegovy, Zepbound)
- Wegovy/Zepbound pricing isn't shown upfront — depends on insurance at the prescribing visit
Graded #374 · C
Strengths
- Compounded semaglutide from $150/mo including medication and refrigerated home shipping — no hidden fees stated on site
- Backed by 64-clinic chain operating across 10 states with medical providers for in-person or telehealth care
- Telehealth consultations from home; $100 initial visit, $40 follow-up every 1–3 months
- Nutrition counseling and lifestyle planning included as part of personalized treatment program
- Free weight-loss consultation option available before committing to paid evaluation
Where it loses points
- Telehealth GLP-1 program currently Texas-only; rolling out more states but no timeline published
- Tirzepatide not confirmed for online program; only compounded semaglutide explicitly listed
- Labs not included or mentioned; no baseline bloodwork protocol disclosed on website
- Dose-escalation pricing not published; $150/mo is entry dose only, higher doses may cost more
- No LegitScript, named medical director, or publicly disclosed compounding pharmacy partner found
Also worth a look
Neither is our top-graded pick — CoreAge Rx leads the scorecard
Across all 499 providers, CoreAge Rx grades highest at 91.8/100 (A−). Top of the scorecard: flat transparent pricing, both molecules, nationwide — no teaser-rate games.
Pricing/verification reflect each provider's public disclosures at last grading; the WeighScore is our editorial judgment per the methodology. Prices change — confirm on each provider's site. Not medical advice; see our disclosure.