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Head-to-head · WeighScore

Amazon One Medical vs Piper

Amazon One Medical
Graded #45

Lower grade

vs+4.400000000000006
Piper
Graded #34

Higher grade

The verdict

Piper takes it — 81.9/100 to 77.5/100.

Piper grades higher on WeighScore, our editorial score across cost value, dose & formulation, clinical oversight, labs & monitoring, fulfillment and contract terms. Mid-value both-molecule pricing ($135/$199), nationwide, though not verified.

We may earn a commission if you start care through some of these links, at no extra cost to you. It never moves the WeighScore, which is the weighted average of the six factors shown for every provider, and what we write about a provider is the same either way. See our disclosure.

Factor by factor

The same six graded dimensions, side by side. See the methodology.

Cost valuePiper +6
80
86
Dose & formulationPiper +22
58
80
Clinical oversightAmazon One Medical +13
92
79
Labs & monitoringEven
78
78
FulfillmentAmazon One Medical +9
95
86
Contract termsPiper +27
55
82
Amazon One Medical · left barPiper · right bar

The numbers

MetricAmazon One MedicalPiper
WeighScore77.5/10081.9/100
GradeC+B−
Scorecard rank#45#34
SemaglutideNot disclosed$135/mo
TirzepatideNot disclosed$199/mo
CoverageAll 50 statesAll 50 states
Brand-name accessYesCompounded only
Oral / sublingualInjection onlyInjection only
Amazon One Medical

Graded #45 · C+

Strengths

  • As low as $1/day ($25/month) for brand-name Foundayo with insurance and the auto-applied Lilly coupon
  • Same-day delivery in nearly 3,000 US cities at launch, expanding to 4,500 by end of 2026
  • In-office pharmacist kiosks at select One Medical clinics let you walk out with Foundayo in hand
  • Cash-pay $5/day ($149/month) is competitive for the same FDA-approved brand-name product
  • Real-time availability, transparent pricing, and automatic manufacturer coupon at checkout

Where it loses points

  • Headline $25/month needs both insurance and the Lilly Savings Card — uninsured pay $149/month
  • Same-day delivery is geographically gated; outside major cities it drops to next-day or slower
  • Pricing is set by manufacturer savings programs and can change at any time
  • No compounded options — brand-name only (Foundayo, Wegovy, Zepbound)
  • Wegovy/Zepbound pricing isn't shown upfront — depends on insurance at the prescribing visit
Piper

Graded #34 · B−

Strengths

  • $135 sema / $199 tirz
  • All 50 states
  • Both molecules

Where it loses points

  • Not LegitScript-verified
  • Injection-only
  • Monitoring detail limited

Also worth a look

Neither is our top-graded pick — CoreAge Rx leads the scorecard

Across all 499 providers, CoreAge Rx grades highest at 91.8/100 (A−). Top of the scorecard: flat transparent pricing, both molecules, nationwide — no teaser-rate games.

Pricing/verification reflect each provider's public disclosures at last grading; the WeighScore is our editorial judgment per the methodology. Prices change — confirm on each provider's site. Not medical advice; see our disclosure.

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