Head-to-head · WeighScore
Amazon One Medical vs Luma Meds
The verdict
Amazon One Medical takes it — 77.5/100 to 57.8/100.
Amazon One Medical grades higher on WeighScore, our editorial score across cost value, dose & formulation, clinical oversight, labs & monitoring, fulfillment and contract terms. Amazon One Medical is the unified Amazon GLP-1 channel — One Medical clinicians prescribe FDA-approved Wegovy, Zepbound, and Foundayo (no compounded products), and Amazon Pharmacy fulfills with same-day…
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Factor by factor
The same six graded dimensions, side by side. See the methodology.
The numbers
| Metric | Amazon One Medical | Luma Meds |
|---|---|---|
| WeighScore | 77.5/100 | 57.8/100 |
| Grade | C+ | C |
| Scorecard rank | #45 | #391 |
| Semaglutide | Not disclosed | $249/mo (compounded) |
| Tirzepatide | Not disclosed | $299/mo (compounded) |
| Coverage | All 50 states | Coverage not published |
| Brand-name access | Yes | Compounded only |
| Oral / sublingual | Injection only | Injection only |
Graded #45 · C+
Strengths
- As low as $1/day ($25/month) for brand-name Foundayo with insurance and the auto-applied Lilly coupon
- Same-day delivery in nearly 3,000 US cities at launch, expanding to 4,500 by end of 2026
- In-office pharmacist kiosks at select One Medical clinics let you walk out with Foundayo in hand
- Cash-pay $5/day ($149/month) is competitive for the same FDA-approved brand-name product
- Real-time availability, transparent pricing, and automatic manufacturer coupon at checkout
Where it loses points
- Headline $25/month needs both insurance and the Lilly Savings Card — uninsured pay $149/month
- Same-day delivery is geographically gated; outside major cities it drops to next-day or slower
- Pricing is set by manufacturer savings programs and can change at any time
- No compounded options — brand-name only (Foundayo, Wegovy, Zepbound)
- Wegovy/Zepbound pricing isn't shown upfront — depends on insurance at the prescribing visit
Graded #391 · C
Strengths
- LegitScript certified — a credibility mark fewer compounded GLP-1 providers carry
- Free discreet shipping and unlimited 24/7 support on every plan
- Compounded semaglutide and tirzepatide from FDA-regulated 503A/503B pharmacies
- '100,000+ members treated' claim with physician-supervised online care
- 3-month bundle pricing brings semaglutide as low as $140/mo
Where it loses points
- Compounding pharmacy partner not publicly named
- States available not published
- Monthly semaglutide ($249/mo) is above many lower-cost compounded competitors
- No oral formulation options listed
- Compounded medications are not FDA-approved
Also worth a look
Neither is our top-graded pick — CoreAge Rx leads the scorecard
Across all 499 providers, CoreAge Rx grades highest at 91.8/100 (A−). Top of the scorecard: flat transparent pricing, both molecules, nationwide — no teaser-rate games.
Pricing/verification reflect each provider's public disclosures at last grading; the WeighScore is our editorial judgment per the methodology. Prices change — confirm on each provider's site. Not medical advice; see our disclosure.