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Head-to-head · WeighScore

AlyveRx vs Silhouette MD

AlyveRx
Graded #103

Higher grade

vs+1.0999999999999943
Silhouette MD
Graded #123

Lower grade

The verdict

AlyveRx takes it — 70.5/100 to 69.4/100, but only just.

AlyveRx grades higher on WeighScore, our editorial score across cost value, dose & formulation, clinical oversight, labs & monitoring, fulfillment and contract terms. AlyveRx (Alyve, Inc.) is a US online telehealth platform connecting patients with licensed providers for GLP-1 weight loss care, no insurance required, with free discreet delivery. Silhouette MD is close behind and may still be the better fit — see the factor split below.

We may earn a commission if you start care through some of these links, at no extra cost to you. It never moves the WeighScore, which is the weighted average of the six factors shown for every provider, and what we write about a provider is the same either way. See our disclosure.

Factor by factor

The same six graded dimensions, side by side. See the methodology.

Cost valueSilhouette MD +5
69
74
Dose & formulationAlyveRx +21
96
75
Clinical oversightSilhouette MD +6
71
77
Labs & monitoringSilhouette MD +2
52
54
FulfillmentSilhouette MD +3
64
67
Contract termsEven
55
55
AlyveRx · left barSilhouette MD · right bar

The numbers

MetricAlyveRxSilhouette MD
WeighScore70.5/10069.4/100
GradeCC
Scorecard rank#103#123
Semaglutide$183/mo (all doses, compounded)$149/mo (compounded)
Tirzepatide$249/mo (all doses, compounded)$299/mo (compounded)
CoverageCoverage not publishedCoverage not published
Brand-name accessYesCompounded only
Oral / sublingualYesYes
AlyveRx

Graded #103 · C

Strengths

  • Offers compounded semaglutide and tirzepatide as both injections and needle-free sublingual drops for people who dislike needles
  • Transparent monthly pricing shown upfront, no insurance required, and free discreet delivery
  • Also carries brand-name Ozempic, Wegovy, and Mounjaro through its provider network

Where it loses points

  • Does not publicly name its dispensing pharmacy or display a LegitScript seal, so third-party accreditation is unverified
  • Sublingual GLP-1 absorption relies on the company proprietary PermeAct technology and is not FDA-reviewed for weight loss
  • State availability is not published on the site
Silhouette MD

Graded #123 · C

Strengths

  • Compounded semaglutide and tirzepatide in both injectable and oral formulations
  • Concierge-level support — monitoring, expert guidance, and check-ins included on every plan
  • Transparent, published pricing starting at $149/mo for semaglutide injection
  • Prescriptions issued and fulfilled by licensed clinical partner OpenLoop Health

Where it loses points

  • Tirzepatide ($299/mo) and oral options ($263–$325/mo) priced above many compounded competitors
  • State availability not published
  • Newer brand with limited independent review history
  • Medications are compounded, not FDA-approved brand-name

Also worth a look

Neither is our top-graded pick — CoreAge Rx leads the scorecard

Across all 499 providers, CoreAge Rx grades highest at 91.8/100 (A−). Top of the scorecard: flat transparent pricing, both molecules, nationwide — no teaser-rate games.

Pricing/verification reflect each provider's public disclosures at last grading; the WeighScore is our editorial judgment per the methodology. Prices change — confirm on each provider's site. Not medical advice; see our disclosure.

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