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Head-to-head · WeighScore

AlyveRx vs Onyx Weight Loss

AlyveRx
Graded #107

Higher grade

vs+11.5
Onyx Weight Loss
Graded #358

Lower grade

The verdict

AlyveRx takes it — 70.3/100 to 58.8/100.

AlyveRx grades higher on WeighScore, our editorial score across cost value, dose & formulation, clinical oversight, labs & monitoring, fulfillment and contract terms. AlyveRx (Alyve, Inc.) is a US online telehealth platform connecting patients with licensed providers for GLP-1 weight loss care, no insurance required, with free discreet delivery.

We may earn a commission if you start care through some of these links, at no extra cost to you. It never moves the WeighScore, which is the weighted average of the six factors shown for every provider, and what we write about a provider is the same either way. See our disclosure.

Factor by factor

The same six graded dimensions, side by side. See the methodology.

Cost valueAlyveRx +25
68
43
Dose & formulationAlyveRx +32
96
64
Clinical oversightOnyx Weight Loss +4
71
75
Labs & monitoringOnyx Weight Loss +11
52
63
FulfillmentAlyveRx +11
64
53
Contract termsEven
55
55
AlyveRx · left barOnyx Weight Loss · right bar

The numbers

MetricAlyveRxOnyx Weight Loss
WeighScore70.3/10058.8/100
GradeCC
Scorecard rank#107#358
Semaglutide$183/mo (all doses, compounded)$228/mo (starting dose, compounded)
Tirzepatide$249/mo (all doses, compounded)$280/mo (starting dose, compounded)
CoverageCoverage not published8 states
Brand-name accessYesCompounded only
Oral / sublingualYesInjection only
AlyveRx

Graded #107 · C

Strengths

  • Offers compounded semaglutide and tirzepatide as both injections and needle-free sublingual drops for people who dislike needles
  • Transparent monthly pricing shown upfront, no insurance required, and free discreet delivery
  • Also carries brand-name Ozempic, Wegovy, and Mounjaro through its provider network

Where it loses points

  • Does not publicly name its dispensing pharmacy or display a LegitScript seal, so third-party accreditation is unverified
  • Sublingual GLP-1 absorption relies on the company proprietary PermeAct technology and is not FDA-reviewed for weight loss
  • State availability is not published on the site
Onyx Weight Loss

Graded #358 · C

Strengths

  • Competitive entry pricing: semaglutide from $228/mo and tirzepatide from $280/mo with medication + supplies included
  • Nurse-practitioner-led care: founder Tasha Vangile FNP-C (20+ years) and Stephanie Robison APRN-CNP (27 years experience)
  • Low-cost $99/mo GLP-1 microdosing option for patients who prefer a gradual titration start
  • Strive Pharmacy partnership implies compounded 503A-quality supply chain from a known pharmacy
  • Multi-modal clinic: GLP-1 + peptides + HRT + nutrition coaching available under one provider team

Where it loses points

  • Only 8 states (NC, CO, ME, VT, VA, IA, NH, PA) — excludes the majority of the US
  • No LegitScript certification; credentialing evidence limited to local 2025 Best of Iredell award
  • Specific drug names (semaglutide/tirzepatide) never stated on website; compounded status inferred, not disclosed
  • Labs not included or mentioned; no baseline bloodwork protocol published
  • Pricing shown as 'Starting at' with no dose-escalation tier pricing disclosed publicly

Also worth a look

Neither is our top-graded pick — CoreAge Rx leads the scorecard

Across all 499 providers, CoreAge Rx grades highest at 91.8/100 (A−). Top of the scorecard: flat transparent pricing, both molecules, nationwide — no teaser-rate games.

Pricing/verification reflect each provider's public disclosures at last grading; the WeighScore is our editorial judgment per the methodology. Prices change — confirm on each provider's site. Not medical advice; see our disclosure.

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