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Head-to-head · WeighScore

AlyveRx vs Lyfe Rx

AlyveRx
Graded #103

Higher grade

vs+12.200000000000003
Lyfe Rx
Graded #375

Lower grade

The verdict

AlyveRx takes it — 70.5/100 to 58.3/100.

AlyveRx grades higher on WeighScore, our editorial score across cost value, dose & formulation, clinical oversight, labs & monitoring, fulfillment and contract terms. AlyveRx (Alyve, Inc.) is a US online telehealth platform connecting patients with licensed providers for GLP-1 weight loss care, no insurance required, with free discreet delivery.

We may earn a commission if you start care through some of these links, at no extra cost to you. It never moves the WeighScore, which is the weighted average of the six factors shown for every provider, and what we write about a provider is the same either way. See our disclosure.

Factor by factor

The same six graded dimensions, side by side. See the methodology.

Cost valueAlyveRx +19
69
50
Dose & formulationAlyveRx +32
96
64
Clinical oversightAlyveRx +4
71
67
Labs & monitoringEven
52
52
FulfillmentAlyveRx +2
64
62
Contract termsEven
55
55
AlyveRx · left barLyfe Rx · right bar

The numbers

MetricAlyveRxLyfe Rx
WeighScore70.5/10058.3/100
GradeCC
Scorecard rank#103#375
Semaglutide$183/mo (all doses, compounded)$225/mo (compounded)
Tirzepatide$249/mo (all doses, compounded)$299/mo (compounded)
CoverageCoverage not publishedCoverage not published
Brand-name accessYesCompounded only
Oral / sublingualYesInjection only
AlyveRx

Graded #103 · C

Strengths

  • Offers compounded semaglutide and tirzepatide as both injections and needle-free sublingual drops for people who dislike needles
  • Transparent monthly pricing shown upfront, no insurance required, and free discreet delivery
  • Also carries brand-name Ozempic, Wegovy, and Mounjaro through its provider network

Where it loses points

  • Does not publicly name its dispensing pharmacy or display a LegitScript seal, so third-party accreditation is unverified
  • Sublingual GLP-1 absorption relies on the company proprietary PermeAct technology and is not FDA-reviewed for weight loss
  • State availability is not published on the site
Lyfe Rx

Graded #375 · C

Strengths

  • Both compounded semaglutide and tirzepatide available
  • Delivery to all 50 states with 1–3 day pharmacy turnaround

Where it loses points

  • No visible LegitScript or PCAB accreditation
  • Also sells non-prescription supplements ('Tirzepatide Weight Loss Supplement', 'Lipo Burn')
  • Shopify-based e-commerce storefront — less clinical infrastructure
  • FDA issued this company a warning letter dated 9 September 2025; the letter is public in FDA's warning-letter database

Also worth a look

Neither is our top-graded pick — CoreAge Rx leads the scorecard

Across all 499 providers, CoreAge Rx grades highest at 91.8/100 (A−). Top of the scorecard: flat transparent pricing, both molecules, nationwide — no teaser-rate games.

Pricing/verification reflect each provider's public disclosures at last grading; the WeighScore is our editorial judgment per the methodology. Prices change — confirm on each provider's site. Not medical advice; see our disclosure.

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