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Head-to-head · WeighScore

Alegro Health vs Ryze Rx

Alegro Health
Graded #351

Higher grade

vs+0.6999999999999957
Ryze Rx
Graded #376

Lower grade

The verdict

Alegro Health takes it — 58.9/100 to 58.2/100, but only just.

Alegro Health grades higher on WeighScore, our editorial score across cost value, dose & formulation, clinical oversight, labs & monitoring, fulfillment and contract terms. Alegro Health is a HIPAA telehealth practice based in McKinney, Texas that offers a low-cost compounded semaglutide weight-loss starter. Ryze Rx is close behind and may still be the better fit — see the factor split below.

We may earn a commission if you start care through some of these links, at no extra cost to you. It never moves the WeighScore, which is the weighted average of the six factors shown for every provider, and what we write about a provider is the same either way. See our disclosure.

Factor by factor

The same six graded dimensions, side by side. See the methodology.

Cost valueAlegro Health +10
54
44
Dose & formulationRyze Rx +12
52
64
Clinical oversightRyze Rx +5
70
75
Labs & monitoringAlegro Health +10
62
52
FulfillmentRyze Rx +12
57
69
Contract termsAlegro Health +20
61
41
Alegro Health · left barRyze Rx · right bar

The numbers

MetricAlegro HealthRyze Rx
WeighScore58.9/10058.2/100
GradeCC
Scorecard rank#351#376
Semaglutide$199/mo (starting dose, compounded)$199/mo (starting dose, 3 month plan, compounded)
TirzepatideNot disclosed$199/mo (starting dose, 3 month plan, compounded)
CoverageCoverage not publishedCoverage not published
Brand-name accessCompounded onlyCompounded only
Oral / sublingualInjection onlyInjection only
Alegro Health

Graded #351 · C

Strengths

  • Low-cost entry point: 199 dollars for a full 8-week semaglutide starter with B12
  • Direct shipping with no recurring monthly fees
  • Operates from a physical Texas medical practice with a published phone number

Where it loses points

  • Semaglutide only; no tirzepatide offered
  • Available in select states only, which are not enumerated
  • Thin public information and compounding pharmacy not named on the site
Ryze Rx

Graded #376 · C

Strengths

  • Compounded semaglutide and tirzepatide both $199/mo, with $499/$799 three-month bundles
  • Physician consultation, ongoing clinical support and discreet shipping included with each prescription
  • Broad catalog beyond GLP-1: TRT plus peptides (BPC-157, sermorelin, NAD+, retatrutide and more)
  • Free shipping, 24hr prescription turnaround, FSA/HSA eligible; care advertised in all 50 states

Where it loses points

  • Terms, Privacy Policy and HIPAA notice are dead links - no legal entity, refund policy or governing law disclosed
  • Pharmacy partners not named - only 'US-licensed compounding pharmacies'
  • Homepage advertises GLP-1s 'from $149/mo' but the catalog lists $199/mo
  • On-site '4.9/5, 2,400+ reviews' is self-reported, not an independently verified rating

Also worth a look

Neither is our top-graded pick — CoreAge Rx leads the scorecard

Across all 499 providers, CoreAge Rx grades highest at 91.8/100 (A−). Top of the scorecard: flat transparent pricing, both molecules, nationwide — no teaser-rate games.

Pricing/verification reflect each provider's public disclosures at last grading; the WeighScore is our editorial judgment per the methodology. Prices change — confirm on each provider's site. Not medical advice; see our disclosure.

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