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Head-to-head · WeighScore

Alegro Health vs Lyfe Rx

Alegro Health
Graded #352

Higher grade

vs+0.6000000000000014
Lyfe Rx
Graded #375

Lower grade

The verdict

Alegro Health takes it — 58.9/100 to 58.3/100, but only just.

Alegro Health grades higher on WeighScore, our editorial score across cost value, dose & formulation, clinical oversight, labs & monitoring, fulfillment and contract terms. Alegro Health is a HIPAA telehealth practice based in McKinney, Texas that offers a low-cost compounded semaglutide weight-loss starter. Lyfe Rx is close behind and may still be the better fit — see the factor split below.

We may earn a commission if you start care through some of these links, at no extra cost to you. It never moves the WeighScore, which is the weighted average of the six factors shown for every provider, and what we write about a provider is the same either way. See our disclosure.

Factor by factor

The same six graded dimensions, side by side. See the methodology.

Cost valueAlegro Health +4
54
50
Dose & formulationLyfe Rx +12
52
64
Clinical oversightAlegro Health +3
70
67
Labs & monitoringAlegro Health +10
62
52
FulfillmentLyfe Rx +5
57
62
Contract termsAlegro Health +6
61
55
Alegro Health · left barLyfe Rx · right bar

The numbers

MetricAlegro HealthLyfe Rx
WeighScore58.9/10058.3/100
GradeCC
Scorecard rank#352#375
Semaglutide$199/mo (starting dose, compounded)$225/mo (compounded)
TirzepatideNot disclosed$299/mo (compounded)
CoverageCoverage not publishedCoverage not published
Brand-name accessCompounded onlyCompounded only
Oral / sublingualInjection onlyInjection only
Alegro Health

Graded #352 · C

Strengths

  • Low-cost entry point: 199 dollars for a full 8-week semaglutide starter with B12
  • Direct shipping with no recurring monthly fees
  • Operates from a physical Texas medical practice with a published phone number

Where it loses points

  • Semaglutide only; no tirzepatide offered
  • Available in select states only, which are not enumerated
  • Thin public information and compounding pharmacy not named on the site
Lyfe Rx

Graded #375 · C

Strengths

  • Both compounded semaglutide and tirzepatide available
  • Delivery to all 50 states with 1–3 day pharmacy turnaround

Where it loses points

  • No visible LegitScript or PCAB accreditation
  • Also sells non-prescription supplements ('Tirzepatide Weight Loss Supplement', 'Lipo Burn')
  • Shopify-based e-commerce storefront — less clinical infrastructure
  • FDA issued this company a warning letter dated 9 September 2025; the letter is public in FDA's warning-letter database

Also worth a look

Neither is our top-graded pick — CoreAge Rx leads the scorecard

Across all 499 providers, CoreAge Rx grades highest at 91.8/100 (A−). Top of the scorecard: flat transparent pricing, both molecules, nationwide — no teaser-rate games.

Pricing/verification reflect each provider's public disclosures at last grading; the WeighScore is our editorial judgment per the methodology. Prices change — confirm on each provider's site. Not medical advice; see our disclosure.

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