Head-to-head · WeighScore
Actin vs SynergenX Health
The verdict
Actin takes it — 59.1/100 to 58.4/100, but only just.
Actin grades higher on WeighScore, our editorial score across cost value, dose & formulation, clinical oversight, labs & monitoring, fulfillment and contract terms. Actin offers compounded semaglutide with B12 for weight loss. SynergenX Health is close behind and may still be the better fit — see the factor split below.
We may earn a commission if you start care through some of these links, at no extra cost to you. It never moves the WeighScore, which is the weighted average of the six factors shown for every provider, and what we write about a provider is the same either way. See our disclosure.
Factor by factor
The same six graded dimensions, side by side. See the methodology.
The numbers
| Metric | Actin | SynergenX Health |
|---|---|---|
| WeighScore | 59.1/100 | 58.4/100 |
| Grade | C | C |
| Scorecard rank | #349 | #374 |
| Semaglutide | $169/mo (compounded) | $150/mo (starting dose, plus a separate fee, compounded) |
| Tirzepatide | Not disclosed | Not disclosed |
| Coverage | Coverage not published | 10 states |
| Brand-name access | Compounded only | Compounded only |
| Oral / sublingual | Injection only | Injection only |
Graded #349 · C
Strengths
- Semaglutide paired with B12 for added energy support
- Transparent pricing — exact cost shown upfront with no hidden fees
- Competitive pricing from $116/mo on the 6-month plan ($169/mo month-to-month)
Where it loses points
- Semaglutide only — no tirzepatide or liraglutide
- No visible LegitScript or PCAB accreditation
- States served not disclosed
- Broad platform spanning hormones, sexual wellness, and hair health
Graded #374 · C
Strengths
- Compounded semaglutide from $150/mo including medication and refrigerated home shipping — no hidden fees stated on site
- Backed by 64-clinic chain operating across 10 states with medical providers for in-person or telehealth care
- Telehealth consultations from home; $100 initial visit, $40 follow-up every 1–3 months
- Nutrition counseling and lifestyle planning included as part of personalized treatment program
- Free weight-loss consultation option available before committing to paid evaluation
Where it loses points
- Telehealth GLP-1 program currently Texas-only; rolling out more states but no timeline published
- Tirzepatide not confirmed for online program; only compounded semaglutide explicitly listed
- Labs not included or mentioned; no baseline bloodwork protocol disclosed on website
- Dose-escalation pricing not published; $150/mo is entry dose only, higher doses may cost more
- No LegitScript, named medical director, or publicly disclosed compounding pharmacy partner found
Also worth a look
Neither is our top-graded pick — CoreAge Rx leads the scorecard
Across all 499 providers, CoreAge Rx grades highest at 91.8/100 (A−). Top of the scorecard: flat transparent pricing, both molecules, nationwide — no teaser-rate games.
Pricing/verification reflect each provider's public disclosures at last grading; the WeighScore is our editorial judgment per the methodology. Prices change — confirm on each provider's site. Not medical advice; see our disclosure.