Head-to-head · WeighScore
Actin vs Open Water Rx
The verdict
Actin takes it — 59.1/100 to 58.8/100, but only just.
Actin grades higher on WeighScore, our editorial score across cost value, dose & formulation, clinical oversight, labs & monitoring, fulfillment and contract terms. Actin offers compounded semaglutide with B12 for weight loss. Open Water Rx is close behind and may still be the better fit — see the factor split below.
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Factor by factor
The same six graded dimensions, side by side. See the methodology.
The numbers
| Metric | Actin | Open Water Rx |
|---|---|---|
| WeighScore | 59.1/100 | 58.8/100 |
| Grade | C | C |
| Scorecard rank | #349 | #360 |
| Semaglutide | $169/mo (compounded) | $249/mo (compounded) |
| Tirzepatide | Not disclosed | $339/mo (compounded) |
| Coverage | Coverage not published | Coverage not published |
| Brand-name access | Compounded only | Yes |
| Oral / sublingual | Injection only | Yes |
Graded #349 · C
Strengths
- Semaglutide paired with B12 for added energy support
- Transparent pricing — exact cost shown upfront with no hidden fees
- Competitive pricing from $116/mo on the 6-month plan ($169/mo month-to-month)
Where it loses points
- Semaglutide only — no tirzepatide or liraglutide
- No visible LegitScript or PCAB accreditation
- States served not disclosed
- Broad platform spanning hormones, sexual wellness, and hair health
Graded #360 · C
Strengths
- Combines weight-loss and longevity verticals in one brand
- Established brand domain
Where it loses points
- Limited public data — most details are gated behind signup or rendered only in JavaScript
- Pricing not disclosed
- GLP-1 options (semaglutide vs. tirzepatide, compounded vs. brand, injection vs. oral) not stated
- States-served list not disclosed
- Pharmacy partner not named
Also worth a look
Neither is our top-graded pick — CoreAge Rx leads the scorecard
Across all 499 providers, CoreAge Rx grades highest at 91.8/100 (A−). Top of the scorecard: flat transparent pricing, both molecules, nationwide — no teaser-rate games.
Pricing/verification reflect each provider's public disclosures at last grading; the WeighScore is our editorial judgment per the methodology. Prices change — confirm on each provider's site. Not medical advice; see our disclosure.