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Head-to-head · WeighScore

Actin vs HumeCare+

Actin
Graded #349

Higher grade

vs+0.5
HumeCare+
Graded #366

Lower grade

The verdict

Actin takes it — 59.1/100 to 58.6/100, but only just.

Actin grades higher on WeighScore, our editorial score across cost value, dose & formulation, clinical oversight, labs & monitoring, fulfillment and contract terms. Actin offers compounded semaglutide with B12 for weight loss. HumeCare+ is close behind and may still be the better fit — see the factor split below.

We may earn a commission if you start care through some of these links, at no extra cost to you. It never moves the WeighScore, which is the weighted average of the six factors shown for every provider, and what we write about a provider is the same either way. See our disclosure.

Factor by factor

The same six graded dimensions, side by side. See the methodology.

Cost valueActin +6
60
54
Dose & formulationEven
52
52
Clinical oversightActin +8
79
71
Labs & monitoringHumeCare+ +1
52
53
FulfillmentHumeCare+ +2
62
64
Contract termsHumeCare+ +28
33
61
Actin · left barHumeCare+ · right bar

The numbers

MetricActinHumeCare+
WeighScore59.1/10058.6/100
GradeCC
Scorecard rank#349#366
Semaglutide$169/mo (compounded)$199/mo (starting dose, compounded)
TirzepatideNot disclosedNot disclosed
CoverageCoverage not publishedCoverage not published
Brand-name accessCompounded onlyCompounded only
Oral / sublingualInjection onlyInjection only
Actin

Graded #349 · C

Strengths

  • Semaglutide paired with B12 for added energy support
  • Transparent pricing — exact cost shown upfront with no hidden fees
  • Competitive pricing from $116/mo on the 6-month plan ($169/mo month-to-month)

Where it loses points

  • Semaglutide only — no tirzepatide or liraglutide
  • No visible LegitScript or PCAB accreditation
  • States served not disclosed
  • Broad platform spanning hormones, sexual wellness, and hair health
HumeCare+

Graded #366 · C

Strengths

  • Pairs compounded semaglutide with continuous body-composition tracking (lose fat, preserve muscle)
  • Includes a Hume Pod body-composition device at no extra cost
  • From $199/mo, billed monthly, cancel anytime
  • Backed by Hume Health, an established body-composition scale brand
  • Clinician-prescribed and monitored with weekly tracking

Where it loses points

  • Final medication pricing is gated behind an intake quiz
  • Only semaglutide is shown on the marketing site (tirzepatide not confirmed)
  • Prescribing medical group and pharmacy partner not named
  • States of operation not published
  • Not LegitScript-certified (no certification displayed)

Also worth a look

Neither is our top-graded pick — CoreAge Rx leads the scorecard

Across all 499 providers, CoreAge Rx grades highest at 91.8/100 (A−). Top of the scorecard: flat transparent pricing, both molecules, nationwide — no teaser-rate games.

Pricing/verification reflect each provider's public disclosures at last grading; the WeighScore is our editorial judgment per the methodology. Prices change — confirm on each provider's site. Not medical advice; see our disclosure.

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