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Head-to-head · WeighScore

Actin vs Direct Meds

Actin
Graded #349

Lower grade

vs+23.499999999999993
Direct Meds
Graded #19

Higher grade

The verdict

Direct Meds takes it — 82.6/100 to 59.1/100.

Direct Meds grades higher on WeighScore, our editorial score across cost value, dose & formulation, clinical oversight, labs & monitoring, fulfillment and contract terms. One of the few programs offering an oral/sublingual route alongside injectable — semaglutide from ~$179 sublingual (~$297 injectable), tirzepatide ~$224/$399, with an intro promo near $147, all-inclusive and no membership.

We may earn a commission if you start care through some of these links, at no extra cost to you. It never moves the WeighScore, which is the weighted average of the six factors shown for every provider, and what we write about a provider is the same either way. See our disclosure.

Factor by factor

The same six graded dimensions, side by side. See the methodology.

Cost valueDirect Meds +25
60
85
Dose & formulationDirect Meds +36
52
88
Clinical oversightDirect Meds +1
79
80
Labs & monitoringDirect Meds +26
52
78
FulfillmentDirect Meds +18
62
80
Contract termsDirect Meds +47
33
80
Actin · left barDirect Meds · right bar

The numbers

MetricActinDirect Meds
WeighScore59.1/10082.6/100
GradeCB−
Scorecard rank#349#19
Semaglutide$169/mo (compounded)$179/mo
TirzepatideNot disclosed$224/mo
CoverageCoverage not publishedNot publicly listed
Brand-name accessCompounded onlyCompounded only
Oral / sublingualInjection onlyYes
Actin

Graded #349 · C

Strengths

  • Semaglutide paired with B12 for added energy support
  • Transparent pricing — exact cost shown upfront with no hidden fees
  • Competitive pricing from $116/mo on the 6-month plan ($169/mo month-to-month)

Where it loses points

  • Semaglutide only — no tirzepatide or liraglutide
  • No visible LegitScript or PCAB accreditation
  • States served not disclosed
  • Broad platform spanning hormones, sexual wellness, and hair health
Direct Meds

Graded #19 · B−

Strengths

  • Rare oral/sublingual option in addition to injectable
  • All-inclusive pricing with no separate membership fee
  • Both molecules — semaglutide and tirzepatide
  • Intro promotional pricing near $147

Where it loses points

  • Compounded only — not FDA-approved
  • Pricing is company-stated, not independently live-verified
  • Newer and somewhat ambiguous (operates across multiple domains)
  • States served are not disclosed

Also worth a look

Neither is our top-graded pick — CoreAge Rx leads the scorecard

Across all 499 providers, CoreAge Rx grades highest at 91.8/100 (A−). Top of the scorecard: flat transparent pricing, both molecules, nationwide — no teaser-rate games.

Pricing/verification reflect each provider's public disclosures at last grading; the WeighScore is our editorial judgment per the methodology. Prices change — confirm on each provider's site. Not medical advice; see our disclosure.

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