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Head-to-head · WeighScore

Actin vs Avono Health

Actin
Graded #349

Higher grade

vs+0.3999999999999986
Avono Health
Graded #361

Lower grade

The verdict

Actin takes it — 59.1/100 to 58.7/100, but only just.

Actin grades higher on WeighScore, our editorial score across cost value, dose & formulation, clinical oversight, labs & monitoring, fulfillment and contract terms. Actin offers compounded semaglutide with B12 for weight loss. Avono Health is close behind and may still be the better fit — see the factor split below.

We may earn a commission if you start care through some of these links, at no extra cost to you. It never moves the WeighScore, which is the weighted average of the six factors shown for every provider, and what we write about a provider is the same either way. See our disclosure.

Factor by factor

The same six graded dimensions, side by side. See the methodology.

Cost valueActin +30
60
30
Dose & formulationAvono Health +23
52
75
Clinical oversightAvono Health +1
79
80
Labs & monitoringAvono Health +1
52
53
FulfillmentAvono Health +9
62
71
Contract termsAvono Health +14
33
47
Actin · left barAvono Health · right bar

The numbers

MetricActinAvono Health
WeighScore59.1/10058.7/100
GradeCC
Scorecard rank#349#361
Semaglutide$169/mo (compounded)$269/mo (compounded)
TirzepatideNot disclosed$349/mo (compounded)
CoverageCoverage not publishedCoverage not published
Brand-name accessCompounded onlyCompounded only
Oral / sublingualInjection onlyYes
Actin

Graded #349 · C

Strengths

  • Semaglutide paired with B12 for added energy support
  • Transparent pricing — exact cost shown upfront with no hidden fees
  • Competitive pricing from $116/mo on the 6-month plan ($169/mo month-to-month)

Where it loses points

  • Semaglutide only — no tirzepatide or liraglutide
  • No visible LegitScript or PCAB accreditation
  • States served not disclosed
  • Broad platform spanning hormones, sexual wellness, and hair health
Avono Health

Graded #361 · C

Strengths

  • Transparent tiered pricing from $179/mo (microdose semaglutide injection)
  • Full compounded range — semaglutide and tirzepatide, injection and oral, microdose and standard
  • Free and discreet shipping; 24/7/365 messaging support; 100% online
  • US-licensed clinicians and pharmacies; bundle discounts at 3/6/12 months

Where it loses points

  • Medications are compounded, not FDA-approved brand-name
  • Compounding pharmacy not publicly named
  • State availability not published
  • Newer brand with limited independent review history

Also worth a look

Neither is our top-graded pick — CoreAge Rx leads the scorecard

Across all 499 providers, CoreAge Rx grades highest at 91.8/100 (A−). Top of the scorecard: flat transparent pricing, both molecules, nationwide — no teaser-rate games.

Pricing/verification reflect each provider's public disclosures at last grading; the WeighScore is our editorial judgment per the methodology. Prices change — confirm on each provider's site. Not medical advice; see our disclosure.

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