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Head-to-head · WeighScore

yourEra vs RxSpan MD

yourEra
Graded #23

Lower grade

vs+2
RxSpan MD
Graded #10

Higher grade

The verdict

RxSpan MD takes it — 86/100 to 84/100, but only just.

RxSpan MD grades higher on WeighScore, our editorial score across cost value, dose & formulation, clinical oversight, labs & monitoring, fulfillment and contract terms. A physician-led telehealth under board-certified founder Dr. John Diaz with a broad GLP-1 menu — compounded semaglutide and tirzepatide by injection or oral capsule, plus a brand-name lane and microdosing — on transparent all-inclusive pricing to all 50 states. yourEra is close behind and may still be the better fit — see the factor split below.

Assume any provider we list may compensate us — we may earn a commission at no cost to you. It never changes the WeighScore.

Factor by factor

The same six graded dimensions, side by side. See the methodology.

Cost valueRxSpan MD +4
82
86
Dose & formulationRxSpan MD +7
82
89
Clinical oversightRxSpan MD +3
85
88
Labs & monitoringyourEra +2
85
83
FulfillmentRxSpan MD +3
86
89
Contract termsEven
85
85
yourEra · left barRxSpan MD · right bar

The numbers

MetricyourEraRxSpan MD
WeighScore84/10086/100
GradeBB
Scorecard rank#23#10
Semaglutide$199/moFrom $194/mo
Tirzepatide$299/mo$329/mo
CoverageAll 50 statesAll 50 states
Brand-name accessCompounded onlyYes
Oral / sublingualInjection onlyYes
yourEra

Graded #23 · B

Strengths

  • Transparent, publicly listed pricing — many compounded competitors hide price behind a quiz
  • Both semaglutide and tirzepatide, not a single-drug menu, plus NAD+ and microdosing lines
  • Markets a 50-state licensed-clinician network; no insurance required, HSA/FSA accepted
  • Optional yourEra Optimum membership adds 1:1 coaching, a nutritionist, at-home lab draws and wearables

Where it loses points

  • Compounded semaglutide/tirzepatide are not FDA-approved (not the same as Wegovy/Ozempic/Zepbound)
  • Mid-market pricing ($199 sema / $299 tirz) — above the cheapest compounders
  • No brand-name lane and no oral route — weekly injectable only
  • Thin independent footprint; the 50-state and efficacy claims are self-reported
RxSpan MD

Graded #10 · B

Strengths

  • Available in all 50 states
  • Transparent, all-inclusive published pricing — consult, medication, supplies, shipping and support, cancel anytime, from ~$194/mo compounded semaglutide on an annual plan
  • Both injectable and a real oral (capsule) route, plus compounded and an advertised brand-name lane
  • Physician-led by a named, board-certified founder (Dr. John Diaz) with 24/7 messaging and coaching

Where it loses points

  • Compounded semaglutide/tirzepatide are not FDA-approved (not the same as Wegovy/Ozempic/Zepbound)
  • Published pricing is for the compounded line — brand-name pricing isn’t itemized
  • A prescription isn’t guaranteed — a provider reviews eligibility after checkout

Also worth a look

Neither is our top-graded pick — CoreAge Rx leads the scorecard

Across all 34 providers, CoreAge Rx grades highest at 94/100 (A). Top of the scorecard: flat transparent pricing, both molecules, nationwide — no teaser-rate games.

Pricing/verification reflect each provider's public disclosures at last grading; the WeighScore is our editorial judgment per the methodology. Prices change — confirm on each provider's site. Not medical advice; see our disclosure.

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