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Head-to-head · WeighScore

telos rx vs Direct Meds

telos rx
Graded #15

Higher grade

vs+3
Direct Meds
Graded #30

Lower grade

The verdict

telos rx takes it — 85/100 to 82/100.

telos rx grades higher on WeighScore, our editorial score across cost value, dose & formulation, clinical oversight, labs & monitoring, fulfillment and contract terms. A LegitScript-certified, HIPAA telehealth with one of the deepest published catalogs on the board — compounded semaglutide and tirzepatide (oral and microdosed routes included) alongside PT-141, intranasal NAD+, and a long recovery/GH peptide bench — with compounded GLP-1 starting from $49/mo on an annual plan.

Assume any provider we list may compensate us — we may earn a commission at no cost to you. It never changes the WeighScore.

Factor by factor

The same six graded dimensions, side by side. See the methodology.

Cost valuetelos rx +2
87
85
Dose & formulationtelos rx +2
90
88
Clinical oversighttelos rx +4
84
80
Labs & monitoringtelos rx +2
80
78
Fulfillmenttelos rx +7
87
80
Contract termsEven
80
80
telos rx · left barDirect Meds · right bar

The numbers

Metrictelos rxDirect Meds
WeighScore85/10082/100
GradeBB−
Scorecard rank#15#30
SemaglutideFrom $49/mo (annual)$179/mo
Tirzepatide$99/mo (annual)$224/mo
CoverageNot publicly listedNot publicly listed
Brand-name accessCompounded onlyCompounded only
Oral / sublingualYesYes
telos rx

Graded #15 · B

Strengths

  • Deep published catalog — sema, tirz, PT-141, intranasal NAD+, recovery/GH peptides, GHK-Cu, Dihexa, HRT
  • Needle-free and oral GLP-1 options, not injection-only
  • LegitScript-certified and HIPAA, with US providers and pharmacies, HSA/FSA and free shipping
  • Low GLP-1 entry — from $49/mo microdosed on an annual plan

Where it loses points

  • Everything is compounded and not FDA-approved, including the peptides
  • Pricing is opaque outside GLP-1 and the lowest rates require annual lock-in
  • No named clinicians and thin third-party reviews
  • Several research-grade peptides carry limited clinical evidence
Direct Meds

Graded #30 · B−

Strengths

  • Rare oral/sublingual option in addition to injectable
  • All-inclusive pricing with no separate membership fee
  • Both molecules — semaglutide and tirzepatide
  • Intro promotional pricing near $147

Where it loses points

  • Compounded only — not FDA-approved
  • Pricing is company-stated, not independently live-verified
  • Newer and somewhat ambiguous (operates across multiple domains)
  • States served are not disclosed

Also worth a look

Neither is our top-graded pick — CoreAge Rx leads the scorecard

Across all 34 providers, CoreAge Rx grades highest at 94/100 (A). Top of the scorecard: flat transparent pricing, both molecules, nationwide — no teaser-rate games.

Pricing/verification reflect each provider's public disclosures at last grading; the WeighScore is our editorial judgment per the methodology. Prices change — confirm on each provider's site. Not medical advice; see our disclosure.

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