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Head-to-head · WeighScore

RxSpan MD vs Direct Meds

RxSpan MD
Graded #10

Higher grade

vs+4
Direct Meds
Graded #30

Lower grade

The verdict

RxSpan MD takes it — 86/100 to 82/100.

RxSpan MD grades higher on WeighScore, our editorial score across cost value, dose & formulation, clinical oversight, labs & monitoring, fulfillment and contract terms. A physician-led telehealth under board-certified founder Dr. John Diaz with a broad GLP-1 menu — compounded semaglutide and tirzepatide by injection or oral capsule, plus a brand-name lane and microdosing — on transparent all-inclusive pricing to all 50 states.

Assume any provider we list may compensate us — we may earn a commission at no cost to you. It never changes the WeighScore.

Factor by factor

The same six graded dimensions, side by side. See the methodology.

Cost valueRxSpan MD +1
86
85
Dose & formulationRxSpan MD +1
89
88
Clinical oversightRxSpan MD +8
88
80
Labs & monitoringRxSpan MD +5
83
78
FulfillmentRxSpan MD +9
89
80
Contract termsRxSpan MD +5
85
80
RxSpan MD · left barDirect Meds · right bar

The numbers

MetricRxSpan MDDirect Meds
WeighScore86/10082/100
GradeBB−
Scorecard rank#10#30
SemaglutideFrom $194/mo$179/mo
Tirzepatide$329/mo$224/mo
CoverageAll 50 statesNot publicly listed
Brand-name accessYesCompounded only
Oral / sublingualYesYes
RxSpan MD

Graded #10 · B

Strengths

  • Available in all 50 states
  • Transparent, all-inclusive published pricing — consult, medication, supplies, shipping and support, cancel anytime, from ~$194/mo compounded semaglutide on an annual plan
  • Both injectable and a real oral (capsule) route, plus compounded and an advertised brand-name lane
  • Physician-led by a named, board-certified founder (Dr. John Diaz) with 24/7 messaging and coaching

Where it loses points

  • Compounded semaglutide/tirzepatide are not FDA-approved (not the same as Wegovy/Ozempic/Zepbound)
  • Published pricing is for the compounded line — brand-name pricing isn’t itemized
  • A prescription isn’t guaranteed — a provider reviews eligibility after checkout
Direct Meds

Graded #30 · B−

Strengths

  • Rare oral/sublingual option in addition to injectable
  • All-inclusive pricing with no separate membership fee
  • Both molecules — semaglutide and tirzepatide
  • Intro promotional pricing near $147

Where it loses points

  • Compounded only — not FDA-approved
  • Pricing is company-stated, not independently live-verified
  • Newer and somewhat ambiguous (operates across multiple domains)
  • States served are not disclosed

Also worth a look

Neither is our top-graded pick — CoreAge Rx leads the scorecard

Across all 34 providers, CoreAge Rx grades highest at 94/100 (A). Top of the scorecard: flat transparent pricing, both molecules, nationwide — no teaser-rate games.

Pricing/verification reflect each provider's public disclosures at last grading; the WeighScore is our editorial judgment per the methodology. Prices change — confirm on each provider's site. Not medical advice; see our disclosure.

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