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Head-to-head · WeighScore

Direct Meds vs Trimi

Direct Meds
Graded #27

Lower grade

vs+4
Trimi
Graded #6

Higher grade

The verdict

Trimi takes it — 86/100 to 82/100.

Trimi grades higher on WeighScore, our editorial score across cost value, dose & formulation, clinical oversight, labs & monitoring, fulfillment and contract terms. Bottom-quartile pricing on both molecules under one flat membership, shipped free nationwide — a strong-value pick sitting just behind the top tier.

Assume any provider we list may compensate us — we may earn a commission at no cost to you. It never changes the WeighScore.

Factor by factor

The same six graded dimensions, side by side. See the methodology.

Cost valueTrimi +8
85
93
Dose & formulationDirect Meds +4
88
84
Clinical oversightTrimi +2
80
82
Labs & monitoringTrimi +5
78
83
FulfillmentTrimi +10
80
90
Contract termsTrimi +4
80
84
Direct Meds · left barTrimi · right bar

The numbers

MetricDirect MedsTrimi
WeighScore82/10086/100
GradeB−B
Scorecard rank#27#6
Semaglutide$179/mo$129/mo
Tirzepatide$224/mo$199/mo
CoverageNot publicly listedAll 50 states
Brand-name accessCompounded onlyCompounded only
Oral / sublingualYesInjection only
Direct Meds

Graded #27 · B−

Strengths

  • Rare oral/sublingual option in addition to injectable
  • All-inclusive pricing with no separate membership fee
  • Both molecules — semaglutide and tirzepatide
  • Intro promotional pricing near $147

Where it loses points

  • Compounded only — not FDA-approved
  • Pricing is company-stated, not independently live-verified
  • Newer and somewhat ambiguous (operates across multiple domains)
  • States served are not disclosed
Trimi

Graded #6 · B

Strengths

  • Low flat pricing on both semaglutide and tirzepatide
  • Both molecules on a single membership
  • Free shipping to all 50 states
  • Fast dispatch once the prescriber signs off

Where it loses points

  • Compounded only — no brand-name Ozempic/Wegovy or Mounjaro/Zepbound
  • Injection only — no oral or sublingual route
  • Dispensing pharmacy not publicly named
  • Shorter public track record than the incumbents

Also worth a look

Neither is our top-graded pick — CoreAge Rx leads the scorecard

Across all 31 providers, CoreAge Rx grades highest at 94/100 (A). Top of the scorecard: flat transparent pricing, both molecules, nationwide — no teaser-rate games.

Pricing/verification reflect each provider's public disclosures at last grading; the WeighScore is our editorial judgment per the methodology. Prices change — confirm on each provider's site. Not medical advice; see our disclosure.

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