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Head-to-head · WeighScore

Direct Meds vs NewSelf

Direct Meds
Graded #27

Lower grade

vs+3
NewSelf
Graded #11

Higher grade

The verdict

NewSelf takes it — 85/100 to 82/100.

NewSelf grades higher on WeighScore, our editorial score across cost value, dose & formulation, clinical oversight, labs & monitoring, fulfillment and contract terms. Round-$100 semaglutide, $144 tirzepatide, verified and available in all 50 states.

Assume any provider we list may compensate us — we may earn a commission at no cost to you. It never changes the WeighScore.

Factor by factor

The same six graded dimensions, side by side. See the methodology.

Cost valueNewSelf +8
85
93
Dose & formulationDirect Meds +8
88
80
Clinical oversightNewSelf +4
80
84
Labs & monitoringNewSelf +4
78
82
FulfillmentNewSelf +7
80
87
Contract termsNewSelf +5
80
85
Direct Meds · left barNewSelf · right bar

The numbers

MetricDirect MedsNewSelf
WeighScore82/10085/100
GradeB−B
Scorecard rank#27#11
Semaglutide$179/mo$100/mo
Tirzepatide$224/mo$144/mo
CoverageNot publicly listedAll 50 states
Brand-name accessCompounded onlyCompounded only
Oral / sublingualYesInjection only
Direct Meds

Graded #27 · B−

Strengths

  • Rare oral/sublingual option in addition to injectable
  • All-inclusive pricing with no separate membership fee
  • Both molecules — semaglutide and tirzepatide
  • Intro promotional pricing near $147

Where it loses points

  • Compounded only — not FDA-approved
  • Pricing is company-stated, not independently live-verified
  • Newer and somewhat ambiguous (operates across multiple domains)
  • States served are not disclosed
NewSelf

Graded #11 · B

Strengths

  • $100 sema / $144 tirz
  • All 50 states, LegitScript-verified
  • Both molecules

Where it loses points

  • Injection-only
  • Labs/monitoring detail sparse
  • Limited brand history

Also worth a look

Neither is our top-graded pick — CoreAge Rx leads the scorecard

Across all 31 providers, CoreAge Rx grades highest at 94/100 (A). Top of the scorecard: flat transparent pricing, both molecules, nationwide — no teaser-rate games.

Pricing/verification reflect each provider's public disclosures at last grading; the WeighScore is our editorial judgment per the methodology. Prices change — confirm on each provider's site. Not medical advice; see our disclosure.

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